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Tor2a Gene Detail
Summary
  • Symbol
    Tor2a
  • Name
    torsin family 2, member A
  • Feature Type
    protein coding gene
  • IDs
    MGI:1353596
    NCBI Gene: 30933
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:32647289-32652256 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 2, 22.09 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    171 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1353596
 protein coding gene Chr2:32647246-32652256 (+)
129S1/SvImJ MGP_129S1SvImJ_G0025622
 protein coding gene Chr2:31249163-31255699 (+)
A/J MGP_AJ_G0025599
 protein coding gene Chr2:29913340-29918848 (+)
AKR/J MGP_AKRJ_G0025569
 protein coding gene Chr2:30987313-30993433 (+)
BALB/cJ MGP_BALBcJ_G0025596
 protein coding gene Chr2:30032452-30037729 (+)
C3H/HeJ MGP_C3HHeJ_G0025356
 protein coding gene Chr2:30870858-30875640 (+)
C57BL/6NJ MGP_C57BL6NJ_G0026040
 protein coding gene Chr2:32185318-32193775 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0023449
 protein coding gene Chr2:28631826-28638012 (+)
CAST/EiJ MGP_CASTEiJ_G0024818
 protein coding gene Chr2:30820738-30826812 (+)
CBA/J MGP_CBAJ_G0025334
 protein coding gene Chr2:33418838-33426406 (+)
DBA/2J MGP_DBA2J_G0025467
 protein coding gene Chr2:29675696-29680763 (+)
FVB/NJ MGP_FVBNJ_G0025429
 protein coding gene Chr2:29562944-29568364 (+)
LP/J MGP_LPJ_G0025553
 protein coding gene Chr2:31123253-31128973 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0025460
 protein coding gene Chr2:33037509-33043051 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0026098
 protein coding gene Chr2:30855733-30861577 (+)
PWK/PhJ MGP_PWKPhJ_G0024566
 protein coding gene Chr2:29583773-29588961 (+)
SPRET/EiJ MGP_SPRETEiJ_G0024366
 protein coding gene Chr2:31016093-31020807 (+)
WSB/EiJ MGP_WSBEiJ_G0024887
 protein coding gene Chr2:31043531-31049490 (+)



Homology
more
  • Human Ortholog
    TOR2A, torsin family 2 member A
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    10
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    721
  • Tissues
    12
  • cDNA Data
    94
  • Literature Summary
    3
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 30933 NCBI Gene Model | MGI Sequence Detail 4968 C57BL/6J ±  kb
transcript NM_001412532 RefSeq | MGI Sequence Detail 2276 C57BL/6  
polypeptide Q8R1J9 UniProt | EBI | MGI Sequence Detail 321 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 95
    cDNA 95

    Microarray probesets 4
References
more
  • Summaries
    All 30
    Developmental Gene Expression 3
    Gene Ontology 5
    Phenotypes 4
  • Earliest
    J:60248 Ozelius LJ, et al., The TOR1A (DYT1) gene family and its role in early onset torsion dystonia. Genomics. 1999 Dec 15;62(3):377-84
  • Latest
    J:226997 Bebee TW, et al., The splicing regulators Esrp1 and Esrp2 direct an epithelial splicing program essential for mammalian development. Elife. 2015;4
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory