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Abt1 Gene Detail
Summary
  • Symbol
    Abt1
  • Name
    activator of basal transcription 1
  • Feature Type
    protein coding gene
  • IDs
    MGI:1353636
    NCBI Gene: 30946
  • Alliance
    gene page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr13:23602531-23608036 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 13, 9.65 cM, cytoband A3.2
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    189 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1353636
 protein coding gene Chr13:23602531-23608036 (-)
129S1/SvImJ MGP_129S1SvImJ_G0020341
 protein coding gene Chr13:20827238-20829561 (-)
A/J MGP_AJ_G0020298
 protein coding gene Chr13:20457425-20459748 (-)
AKR/J MGP_AKRJ_G0020270
 protein coding gene Chr13:20688065-20690388 (-)
BALB/cJ MGP_BALBcJ_G0020284
 protein coding gene Chr13:20448644-20450967 (-)
C3H/HeJ MGP_C3HHeJ_G0020093
 protein coding gene Chr13:20776791-20779114 (-)
C57BL/6NJ MGP_C57BL6NJ_G0020729
 protein coding gene Chr13:21587628-21589955 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0018313
 protein coding gene Chr13:19258840-19261156 (-)
CAST/EiJ MGP_CASTEiJ_G0019614
 protein coding gene Chr13:20463442-20465765 (-)
CBA/J MGP_CBAJ_G0020044
 protein coding gene Chr13:22420294-22422617 (-)
DBA/2J MGP_DBA2J_G0020170
 protein coding gene Chr13:20027179-20029502 (-)
FVB/NJ MGP_FVBNJ_G0020158
 protein coding gene Chr13:19647008-19649331 (-)
LP/J MGP_LPJ_G0020243
 protein coding gene Chr13:21149845-21152167 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0020188
 protein coding gene Chr13:22742159-22744481 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0020759
 protein coding gene Chr13:20550750-20553073 (-)
PWK/PhJ MGP_PWKPhJ_G0019370
 protein coding gene Chr13:20014609-20016979 (-)
SPRET/EiJ MGP_SPRETEiJ_G0019181
 protein coding gene Chr13:19346476-19348802 (-)
WSB/EiJ MGP_WSBEiJ_G0019671
 protein coding gene Chr13:20677077-20679400 (-)



Homology
more
  • Human Ortholog
    ABT1, activator of basal transcription 1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ABT1, activator of basal transcription 1
  • Synonyms
    Esf2, hABT1
  • Links
    NCBI Gene ID: 29777
    neXtProt AC: NX_Q9ULW3
    UniProt: Q9ULW3

  • Chr Location
    6p22.2; chr6:26596953-26600739 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    13 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    12
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    947
  • Tissues
    167
  • cDNA Data
    62
  • Literature Summary
    7
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 30946 NCBI Gene Model | MGI Sequence Detail 5506 C57BL/6J ±  kb
transcript NM_013924 RefSeq | MGI Sequence Detail 4456 C57BL/6  
polypeptide Q9QYL7 UniProt | EBI | MGI Sequence Detail 269 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 63
    cDNA 62
    Primer pair 1

    Microarray probesets 3
References
more
  • Summaries
    All 44
    Developmental Gene Expression 7
    Gene Ontology 5
    Phenotypes 13
  • Earliest
    J:182573 Roderick TH, Producing and detecting paracentric chromosomal inversions in mice. Mutat Res. 1971 Jan;11(1):59-69
  • Latest
    J:215487 Thompson CL, et al., A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain. Neuron. 2014 Jul 16;83(2):309-23
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory