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Synrg Gene Detail
Summary
  • Symbol
    Synrg
  • Name
    synergin, gamma
  • Synonyms
    Ap1gbp1, L71-5
  • Feature Type
    protein coding gene
  • IDs
    MGI:1354742
    NCBI Gene: 217030
  • Alliance
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:83855254-83935404 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 11, 51.25 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    1973 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1354742
protein coding gene Chr11:83855217-83935404 (+)
129S1/SvImJ MGP_129S1SvImJ_G0018864
protein coding gene Chr11:85356557-85441031 (+)
A/J MGP_AJ_G0018831
protein coding gene Chr11:82115511-82196107 (+)
AKR/J MGP_AKRJ_G0018801
protein coding gene Chr11:84536672-84616425 (+)
BALB/cJ MGP_BALBcJ_G0018804
protein coding gene Chr11:82497839-82580893 (+)
C3H/HeJ MGP_C3HHeJ_G0018618
protein coding gene Chr11:84589441-84670593 (+)
C57BL/6NJ MGP_C57BL6NJ_G0019256
protein coding gene Chr11:87944283-88028162 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0016889
protein coding gene Chr11:79205077-79287637 (+)
CAST/EiJ MGP_CASTEiJ_G0018173
protein coding gene Chr11:85220041-85306378 (+)
CBA/J MGP_CBAJ_G0018589
protein coding gene Chr11:91722202-91805782 (+)
DBA/2J MGP_DBA2J_G0018697
protein coding gene Chr11:81692627-81773587 (+)
FVB/NJ MGP_FVBNJ_G0018686
protein coding gene Chr11:81162758-81244853 (+)
LP/J MGP_LPJ_G0018767
protein coding gene Chr11:85893354-85974680 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0018713
protein coding gene Chr11:91867275-91952025 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0019296
protein coding gene Chr11:84818994-84899791 (+)
PWK/PhJ MGP_PWKPhJ_G0017942
protein coding gene Chr11:82446915-82528129 (+)
SPRET/EiJ MGP_SPRETEiJ_G0017734
protein coding gene Chr11:84349290-84437494 (+)
WSB/EiJ MGP_WSBEiJ_G0018224
protein coding gene Chr11:84661588-84744052 (+)



Homology
more
  • Human Ortholog
    SYNRG, synergin gamma
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SYNRG, synergin gamma
  • Synonyms
    AP1GBP1, SYNG
  • Links
    NCBI Gene ID: 11276
    neXtProt AC: NX_Q9UMZ2
    UniProt: Q9UMZ2

  • Chr Location
    17q12; chr17:37514807-37609472 (-)  GRCh38

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    19 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Sequences &
    Gene Models
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    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000034940 Ensembl Gene Model | MGI Sequence Detail 80151 C57BL/6J ±  kb
    transcript ENSMUST00000183456 Ensembl | MGI Sequence Detail 3990 Not Applicable  
    polypeptide ENSMUSP00000138969 Ensembl | MGI Sequence Detail 1329 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 13
      Genomic 1
      cDNA 12

      Microarray probesets 6
    Other
    Accession IDs
    less
    MGI:2144616
    References
    more
    • Summaries
      All 48
      Developmental Gene Expression 2
      Gene Ontology 4
      Phenotypes 19
    • Earliest
      J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    last database update
    11/12/2024
    MGI 6.24
    The Jackson Laboratory