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St6galnac6 Gene Detail
Summary
  • Symbol
    St6galnac6
  • Name
    ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6
  • Synonyms
    Siat7f, ST6GalNAcVI
  • Feature Type
    protein coding gene
  • IDs
    MGI:1355316
    NCBI Gene: 50935
  • Alliance
    gene page
  • Transcription Start Sites
    8 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:32489721-32510818 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 2, 22.09 cM, cytoband B
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    565 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1355316
 protein coding gene Chr2:32489721-32510821 (+)
129S1/SvImJ MGP_129S1SvImJ_G0025614
 protein coding gene Chr2:31075739-31098846 (+)
A/J MGP_AJ_G0025591
 protein coding gene Chr2:29748290-29771470 (+)
AKR/J MGP_AKRJ_G0025561
 protein coding gene Chr2:30813939-30837936 (+)
BALB/cJ MGP_BALBcJ_G0025588
 protein coding gene Chr2:29872820-29893798 (+)
C3H/HeJ MGP_C3HHeJ_G0025348
 protein coding gene Chr2:30701827-30723708 (+)
C57BL/6NJ MGP_C57BL6NJ_G0026032
 protein coding gene Chr2:32017689-32040226 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0023441
 protein coding gene Chr2:28467045-28489830 (+)
CAST/EiJ MGP_CASTEiJ_G0024810
 protein coding gene Chr2:30642456-30663409 (+)
CBA/J MGP_CBAJ_G0025326
 protein coding gene Chr2:33235305-33258828 (+)
DBA/2J MGP_DBA2J_G0025459
 protein coding gene Chr2:29515394-29539125 (+)
FVB/NJ MGP_FVBNJ_G0025421
 protein coding gene Chr2:29391478-29413946 (+)
LP/J MGP_LPJ_G0025545
 protein coding gene Chr2:30951529-30972705 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0025452
 protein coding gene Chr2:32865198-32889824 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0026090
 protein coding gene Chr2:30690731-30712500 (+)
PWK/PhJ MGP_PWKPhJ_G0024558
 protein coding gene Chr2:29421507-29442843 (+)
SPRET/EiJ MGP_SPRETEiJ_G0024358
 protein coding gene Chr2:30845371-30866572 (+)
WSB/EiJ MGP_WSBEiJ_G0024879
 protein coding gene Chr2:30868137-30891190 (+)



Homology
more
  • Human Ortholog
    ST6GALNAC6, ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 6
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ST6GALNAC6, ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 6
  • Synonyms
    SIAT7-F, SIAT7F, ST6GALNACVI
  • Links
    NCBI Gene ID: 30815
    neXtProt AC: NX_Q969X2
    UniProt: Q969X2

  • Chr Location
    9q34.11; chr9:127885321-127906616 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    16
  • GO References
    7
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    854
  • Tissues
    104
  • cDNA Data
    77
  • Literature Summary
    3
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000026811 Ensembl Gene Model | MGI Sequence Detail 21098 C57BL/6J ±  kb
transcript ENSMUST00000081879 Ensembl | MGI Sequence Detail 2345 Not Applicable  
polypeptide ENSMUSP00000080555 Ensembl | MGI Sequence Detail 335 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 80
    cDNA 78
    Primer pair 2

    Microarray probesets 4
References
more
  • Summaries
    All 35
    Developmental Gene Expression 3
    Gene Ontology 7
    Phenotypes 7
  • Earliest
    J:61070 Okajima T, et al., Molecular cloning and expression of mouse GD1alpha/GT1aalpha/GQ1balpha synthase (ST6GalNAc VI) gene. J Biol Chem. 2000 Mar 10;275(10):6717-23
  • Latest
    J:341473 Taniguchi M, et al., Sialylation shapes mucus architecture inhibiting bacterial invasion in the colon. Mucosal Immunol. 2023 Jul 13;
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory