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Snrpa Gene Detail
Summary
  • Symbol
    Snrpa
  • Name
    small nuclear ribonucleoprotein polypeptide A
  • Synonyms
    C430021M15Rik, Rnu1a1, U1A, U1 snRNP
  • Feature Type
    protein coding gene
  • IDs
    MGI:1855690
    NCBI Gene: 53607
  • Alliance
    gene page
  • Transcription Start Sites
    8 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:26886431-26895696 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 7, 15.84 cM, cytoband A3
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    342 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1855690
 protein coding gene Chr7:26886430-26895696 (-)
129S1/SvImJ MGP_129S1SvImJ_G0031901
 protein coding gene Chr7:25804581-25815522 (-)
A/J MGP_AJ_G0031880
 protein coding gene Chr7:25200633-25210134 (-)
AKR/J MGP_AKRJ_G0031810
 protein coding gene Chr7:25865811-25875594 (-)
BALB/cJ MGP_BALBcJ_G0031885
 protein coding gene Chr7:25424246-25433511 (-)
C3H/HeJ MGP_C3HHeJ_G0031607
 protein coding gene Chr7:26247309-26257707 (-)
C57BL/6NJ MGP_C57BL6NJ_G0032350
 protein coding gene Chr7:26660497-26670192 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0029402
 protein coding gene Chr7:26437511-26447297 (-)
CAST/EiJ MGP_CASTEiJ_G0030942
 protein coding gene Chr7:19546317-19556717 (-)
CBA/J MGP_CBAJ_G0031572
 protein coding gene Chr7:27824775-27839381 (-)
DBA/2J MGP_DBA2J_G0031724
 protein coding gene Chr7:25001416-25010922 (-)
FVB/NJ MGP_FVBNJ_G0031680
 protein coding gene Chr7:25084906-25094172 (-)
LP/J MGP_LPJ_G0031804
 protein coding gene Chr7:26146726-26159592 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0031715
 protein coding gene Chr7:27439621-27448433 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0032381
 protein coding gene Chr7:25397615-25407378 (-)
PWK/PhJ MGP_PWKPhJ_G0030666
 protein coding gene Chr7:20031608-20042905 (-)
SPRET/EiJ MGP_SPRETEiJ_G0030500
 protein coding gene Chr7:16386704-16396033 (-)
WSB/EiJ MGP_WSBEiJ_G0031050
 protein coding gene Chr7:25685429-25698312 (-)



Homology
more
  • Human Ortholog
    SNRPA, small nuclear ribonucleoprotein polypeptide A
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SNRPA, small nuclear ribonucleoprotein polypeptide A
  • Synonyms
    Mud1, U1-A, U1A
  • Links
    NCBI Gene ID: 6626
    neXtProt AC: NX_P09012
    UniProt: P09012

  • Chr Location
    19q13.2; chr19:40750637-40765389 (+)  GRCh38
Human Diseases
more
  • Diseases
    1 with human SNRPA associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    25
  • GO References
    6
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    728
  • Tissues
    22
  • cDNA Data
    131
  • Literature Summary
    4
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 53607 NCBI Gene Model | MGI Sequence Detail 9266 C57BL/6J ±  kb
transcript NM_015782 RefSeq | MGI Sequence Detail 1382 C57BL/6  
polypeptide Q62189 UniProt | EBI | MGI Sequence Detail 287 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    4 Sequences
  • Protein Ontology
    PR:000015339 U1 small nuclear ribonucleoprotein A
    (term hierarchy)
  • InterPro Domains
    IPR012677 Nucleotide-binding alpha-beta plait domain superfamily
    IPR035979 RNA-binding domain superfamily
    IPR000504 RNA recognition motif domain
    IPR034407 U1 small nuclear ribonucleoprotein A, RNA recognition motif 1
    IPR034409 U1 small nuclear ribonucleoprotein A, RNA recognition motif 2
  • GlyGen
    Q62189 1 site, 1 O-linked glycan (1 site)
Molecular
Reagents
less
  • All nucleic 133
    cDNA 132
    Primer pair 1

    Microarray probesets 3
Other
Accession IDs
less
MGI:2441904
References
more
  • Summaries
    All 38
    Developmental Gene Expression 4
    Gene Ontology 6
    Phenotypes 7
  • Earliest
    J:15179 Bennett MM, et al., Nucleotide sequence analysis of the A protein of the U1 small nuclear ribonucleoprotein particle: the murine protein contains a 5' amino-terminal tag. Nucleic Acids Res. 1993 Sep 11;21(18):4404
  • Latest
    J:239248 Lee NC, et al., Mutation-adapted U1 snRNA corrects a splicing error of the dopa decarboxylase gene. Hum Mol Genet. 2016 Dec 1;25(23):5142-5147
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory