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Vamp5 Gene Detail
Summary
  • Symbol
    Vamp5
  • Name
    vesicle-associated membrane protein 5
  • Synonyms
    Camp
  • Feature Type
    protein coding gene
  • IDs
    MGI:1858622
    NCBI Gene: 53620
  • Alliance
    gene page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr6:72345777-72357451 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 6, 32.27 cM, cytoband C3
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    236 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1858622
 protein coding gene Chr6:72345032-72357451 (-)
129S1/SvImJ MGP_129S1SvImJ_G0030874
 protein coding gene Chr6:72917678-72929350 (-)
A/J MGP_AJ_G0030844
 protein coding gene Chr6:70090885-70102551 (-)
AKR/J MGP_AKRJ_G0030773
 protein coding gene Chr6:72153270-72164879 (-)
BALB/cJ MGP_BALBcJ_G0030855
 protein coding gene Chr6:70119969-70131585 (-)
C3H/HeJ MGP_C3HHeJ_G0030857
 protein coding gene Chr6:112075248-112087825 (+)
C57BL/6NJ MGP_C57BL6NJ_G0031313
 protein coding gene Chr6:74830127-74842977 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0028502
 protein coding gene Chr6:69236397-69249389 (-)
CAST/EiJ MGP_CASTEiJ_G0029963
 protein coding gene Chr6:72017422-72030854 (-)
CBA/J MGP_CBAJ_G0030542
 protein coding gene Chr6:77880458-77896241 (-)
DBA/2J MGP_DBA2J_G0030694
 protein coding gene Chr6:69486443-69498231 (-)
FVB/NJ MGP_FVBNJ_G0030647
 protein coding gene Chr6:68867994-68885022 (-)
LP/J MGP_LPJ_G0030773
 protein coding gene Chr6:72824955-72837356 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0030682
 protein coding gene Chr6:81270794-81283466 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0031339
 protein coding gene Chr6:71965753-71977429 (-)
PWK/PhJ MGP_PWKPhJ_G0029679
 protein coding gene Chr6:68392356-68404232 (-)
SPRET/EiJ MGP_SPRETEiJ_G0029507
 protein coding gene Chr6:70694918-70706797 (-)
WSB/EiJ MGP_WSBEiJ_G0030045
 protein coding gene Chr6:72329794-72342297 (-)



Homology
more
  • Human Ortholog
    VAMP5, vesicle associated membrane protein 5
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    VAMP5, vesicle associated membrane protein 5
  • Links
    NCBI Gene ID: 10791
    neXtProt AC: NX_O95183
    UniProt: O95183

  • Chr Location
    2p11.2; chr2:85584431-85593406 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    11 phenotypes from 1 allele in 1 genetic background
    8 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a knock-out allele exhibit perinatal lethality, decreased birth weight, duplex ureter, hydroureter, hydronephrosis, and insufficient expansion of the lung.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    15
  • GO References
    10
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    16
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000073002 Ensembl Gene Model | MGI Sequence Detail 11675 C57BL/6J ±  kb
    transcript ENSMUST00000101285 Ensembl | MGI Sequence Detail 623 Not Applicable  
    polypeptide ENSMUSP00000098843 Ensembl | MGI Sequence Detail 102 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 17
      cDNA 17

      Microarray probesets 4
    Other
    Accession IDs
    less
    MGI:2158647
    References
    more
    • Summaries
      All 39
      Gene Ontology 10
      Phenotypes 8
    • Earliest
      J:62055 Zeng Q, et al., A novel synaptobrevin/VAMP homologous protein (VAMP5) is increased during in vitro myogenesis and present in the plasma membrane. Mol Biol Cell. 1998 Sep;9(9):2423-37
    • Latest
      J:330636 Iwata S, et al., An efficient i-GONAD method for creating and maintaining lethal mutant mice using an inversion balancer identified from the C3H/HeJJcl strain. G3 (Bethesda). 2021;11(8)
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    Send questions and comments to User Support.     		last database update
    11/12/2024
    MGI 6.24     		The Jackson Laboratory