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Rundc3a Gene Detail
Summary
  • Symbol
    Rundc3a
  • Name
    RUN domain containing 3A
  • Synonyms
    Rap2ip, Rpip8
  • Feature Type
    protein coding gene
  • IDs
    MGI:1858752
    NCBI Gene: 51799
  • Alliance
    gene page
  • Transcription Start Sites
    6 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:102284229-102293381 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 11, 66.29 cM, cytoband D
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    241 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1858752
 protein coding gene Chr11:102284219-102293381 (+)
129S1/SvImJ MGP_129S1SvImJ_G0019233
 protein coding gene Chr11:105363606-105372752 (+)
A/J MGP_AJ_G0019201
 protein coding gene Chr11:100921447-100930598 (+)
AKR/J MGP_AKRJ_G0019170
 protein coding gene Chr11:104039170-104048322 (+)
BALB/cJ MGP_BALBcJ_G0019175
 protein coding gene Chr11:101403298-101412444 (+)
C3H/HeJ MGP_C3HHeJ_G0018984
 protein coding gene Chr11:104244841-104253987 (+)
C57BL/6NJ MGP_C57BL6NJ_G0019624
 protein coding gene Chr11:108657221-108666373 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0017250
 protein coding gene Chr11:98347573-98356938 (+)
CAST/EiJ MGP_CASTEiJ_G0018538
 protein coding gene Chr11:105237849-105247012 (+)
CBA/J MGP_CBAJ_G0018953
 protein coding gene Chr11:113142164-113151316 (+)
DBA/2J MGP_DBA2J_G0019065
 protein coding gene Chr11:100436076-100445222 (+)
FVB/NJ MGP_FVBNJ_G0019055
 protein coding gene Chr11:99968247-99977399 (+)
LP/J MGP_LPJ_G0019134
 protein coding gene Chr11:105887301-105896447 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0019086
 protein coding gene Chr11:112637052-112646204 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0019662
 protein coding gene Chr11:104408320-104417472 (+)
PWK/PhJ MGP_PWKPhJ_G0018301
 protein coding gene Chr11:101504424-101513585 (+)
SPRET/EiJ MGP_SPRETEiJ_G0018093
 protein coding gene Chr11:104164959-104174110 (+)
WSB/EiJ MGP_WSBEiJ_G0018587
 protein coding gene Chr11:104404044-104413196 (+)



Homology
more
  • Human Ortholog
    RUNDC3A, RUN domain containing 3A
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    RUNDC3A, RUN domain containing 3A
  • Synonyms
    RAP2IP, RPIP-8, RPIP8
  • Links
    NCBI Gene ID: 10900
    neXtProt AC: NX_Q59EK9
    UniProt: Q59EK9

  • Chr Location
    17q21.31; chr17:44308413-44318670 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    15 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    5
  • GO References
    4
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    901
  • Tissues
    52
  • cDNA Data
    6
  • Literature Summary
    5
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000006575 Ensembl Gene Model | MGI Sequence Detail 9153 C57BL/6J ±  kb
transcript ENSMUST00000006750 Ensembl | MGI Sequence Detail 2046 Not Applicable  
polypeptide ENSMUSP00000006750 Ensembl | MGI Sequence Detail 446 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 9
    cDNA 7
    Primer pair 2

    Microarray probesets 6
References
more
  • Summaries
    All 40
    Developmental Gene Expression 5
    Gene Ontology 4
    Phenotypes 15
  • Earliest
    J:60992 Janoueix-Lerosey I, et al., Identification of a specific effector of the small GTP-binding protein Rap2. Eur J Biochem. 1998 Mar 1;252(2):290-8
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory