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Ftsj3 Gene Detail
Summary
  • Symbol
    Ftsj3
  • Name
    FtsJ RNA 2'-O-methyltransferase 3
  • Synonyms
    C79843, D11Ertd400e, Epcs3
  • Feature Type
    protein coding gene
  • IDs
    MGI:1860295
    NCBI Gene: 56095
  • Alliance
    gene page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:106139968-106146905 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 11, 68.89 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    220 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1860295
 protein coding gene Chr11:106139964-106146910 (-)
129S1/SvImJ MGP_129S1SvImJ_G0019299
 protein coding gene Chr11:109538054-109544991 (-)
A/J MGP_AJ_G0019267
 protein coding gene Chr11:104876108-104883045 (-)
AKR/J MGP_AKRJ_G0019236
 protein coding gene Chr11:108003348-108010285 (-)
BALB/cJ MGP_BALBcJ_G0019241
 protein coding gene Chr11:105276840-105283777 (-)
C3H/HeJ MGP_C3HHeJ_G0019050
 protein coding gene Chr11:108292866-108299803 (-)
C57BL/6NJ MGP_C57BL6NJ_G0019691
 protein coding gene Chr11:112888644-112895581 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0017315
 protein coding gene Chr11:102153837-102160691 (-)
CAST/EiJ MGP_CASTEiJ_G0018603
 protein coding gene Chr11:109348548-109355533 (-)
CBA/J MGP_CBAJ_G0019019
 protein coding gene Chr11:117588347-117595284 (-)
DBA/2J MGP_DBA2J_G0019131
 protein coding gene Chr11:104343938-104350875 (-)
FVB/NJ MGP_FVBNJ_G0019122
 protein coding gene Chr11:103845305-103852242 (-)
LP/J MGP_LPJ_G0019201
 protein coding gene Chr11:109977495-109984432 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0019152
 protein coding gene Chr11:116871850-116878787 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0019728
 protein coding gene Chr11:108495834-108502771 (-)
PWK/PhJ MGP_PWKPhJ_G0018368
 protein coding gene Chr11:105440944-105447877 (-)
SPRET/EiJ MGP_SPRETEiJ_G0018159
 protein coding gene Chr11:108258967-108265863 (-)
WSB/EiJ MGP_WSBEiJ_G0018654
 protein coding gene Chr11:108458819-108465756 (-)



Homology
more
  • Human Ortholog
    FTSJ3, FtsJ RNA 2'-O-methyltransferase 3
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    FTSJ3, FtsJ RNA 2'-O-methyltransferase 3
  • Synonyms
    EPCS3, SPB1
  • Links
    NCBI Gene ID: 117246
    neXtProt AC: NX_Q8IY81
    UniProt: Q8IY81

  • Chr Location
    17q23.3; chr17:63819433-63830012 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    20
  • GO References
    6
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    840
  • Tissues
    51
  • cDNA Data
    204
  • Literature Summary
    4
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000020706 Ensembl Gene Model | MGI Sequence Detail 6938 C57BL/6J ±  kb
transcript ENSMUST00000021048 Ensembl | MGI Sequence Detail 3144 Not Applicable  
polypeptide ENSMUSP00000021048 Ensembl | MGI Sequence Detail 838 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    1 Sequence
  • Protein Ontology
    PR:000029729 rRNA methyltransferase 3
    (term hierarchy)
  • EC
    2.1.1.-
  • InterPro Domains
    IPR028589 AdoMet-dependent rRNA methyltransferase SPB1-like
    IPR015507 Ribosomal RNA large subunit methyltransferase E
    IPR050082 Ribosomal RNA large subunit methyltransferase RlmE
    IPR002877 Ribosomal RNA methyltransferase, FtsJ domain
    IPR024576 Ribosomal RNA methyltransferase Spb1, domain of unknown function DUF3381
    IPR012920 Ribosomal RNA methyltransferase, SPB1-like, C-terminal
    IPR029063 S-adenosyl-L-methionine-dependent methyltransferase superfamily
  • GlyGen
    Q9DBE9 1 site, 1 O-linked glycan (1 site)
Molecular
Reagents
less
  • All nucleic 206
    cDNA 204
    Primer pair 2

    Microarray probesets 3
Other
Accession IDs
less
MGI:1196292, MGI:2144025, MGI:2144441, MGI:2144654
References
more
  • Summaries
    All 36
    Developmental Gene Expression 4
    Gene Ontology 6
    Phenotypes 4
  • Earliest
    J:20131 Kerr SM, et al., Analysis of cDNA sequences from mouse testis. Mamm Genome. 1994 Sep;5(9):557-65
  • Latest
    J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory