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Pigp Gene Detail
Summary
  • Symbol
    Pigp
  • Name
    phosphatidylinositol glycan anchor biosynthesis, class P
  • Synonyms
    Dcrc, Dscr5
  • Feature Type
    protein coding gene
  • IDs
    MGI:1860433
    NCBI Gene: 56176
  • Alliance
    gene page
  • Transcription Start Sites
    6 TSS
Location &
Maps
more
  • Sequence Map
    Chr16:94159622-94171874 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 16, 55.18 cM, cytoband C3-C4
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    91 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1860433
 protein coding gene Chr16:94159622-94172701 (-)
129S1/SvImJ MGP_129S1SvImJ_G0023070
 protein coding gene Chr16:95595853-95608078 (-)
A/J MGP_AJ_G0023038
 protein coding gene Chr16:91102010-91108578 (-)
AKR/J MGP_AKRJ_G0023008
 protein coding gene Chr16:93893550-93905750 (-)
BALB/cJ MGP_BALBcJ_G0023040
 protein coding gene Chr16:91638991-91645544 (-)
C3H/HeJ MGP_C3HHeJ_G0022801
 protein coding gene Chr16:94408694-94420892 (-)
C57BL/6NJ MGP_C57BL6NJ_G0023487
 protein coding gene Chr16:98632404-98654979 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0020989
 protein coding gene Chr16:88963831-88970543 (-)
CAST/EiJ MGP_CASTEiJ_G0022320
 protein coding gene Chr16:95152937-95166099 (-)
CBA/J MGP_CBAJ_G0022770
 protein coding gene Chr16:102915785-102930771 (-)
DBA/2J MGP_DBA2J_G0022904
 protein coding gene Chr16:90987032-91000195 (-)
FVB/NJ MGP_FVBNJ_G0022878
 protein coding gene Chr16:90151656-90163938 (-)
LP/J MGP_LPJ_G0022974
 protein coding gene Chr16:95260705-95274371 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0022899
 protein coding gene Chr16:107243100-107255997 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0023505
 protein coding gene Chr16:94411454-94425198 (-)
PWK/PhJ MGP_PWKPhJ_G0022065
 protein coding gene Chr16:91261301-91267822 (-)
SPRET/EiJ MGP_SPRETEiJ_G0021895
 protein coding gene Chr16:93955045-93970470 (-)
WSB/EiJ MGP_WSBEiJ_G0022371
 protein coding gene Chr16:94669143-94676402 (-)



Homology
more
  • Human Ortholog
    PIGP, phosphatidylinositol glycan anchor biosynthesis class P
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    PIGP, phosphatidylinositol glycan anchor biosynthesis class P
  • Synonyms
    DCRC, DCRC-S, DEE55, DSCR5, DSRC, EIEE55, PIG-P
  • Links
    NCBI Gene ID: 51227
    neXtProt AC: NX_P57054
    UniProt: P57054

  • Chr Location
    21q22.13; chr21:37062846-37073170 (-)  GRCh38
Human Diseases
more
  • Diseases
    1 with human PIGP associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

  • References
    6 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    94 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    11
  • GO References
    6
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    890
  • Tissues
    156
  • cDNA Data
    53
  • Literature Summary
    5
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 56176 NCBI Gene Model | MGI Sequence Detail 12253 C57BL/6J ±  kb
transcript NM_001159617 RefSeq | MGI Sequence Detail 942 C57BL/6  
polypeptide Q9JHG1 UniProt | EBI | MGI Sequence Detail 132 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    6 Sequences
  • Protein Ontology
    PR:000012703 phosphatidylinositol N-acetylglucosaminyltransferase subunit P
    (term hierarchy)
  • InterPro Domains
    IPR052263 GPI Anchor Biosynthesis Protein
    IPR031952 KH-like RNA-binding domain
    IPR016542 Phosphatidylinositol N-acetylglucosaminyltransferase, GPI19/PIG-P subunit
    IPR013717 PIG-P
Molecular
Reagents
less
  • All nucleic 56
    cDNA 53
    Primer pair 2
    Other 1

    Microarray probesets 4
References
more
  • Summaries
    All 122
    Developmental Gene Expression 5
    Diseases 6
    Gene Ontology 6
    Phenotypes 94
  • Earliest
    J:42265 Huang TT, et al., Superoxide-mediated cytotoxicity in superoxide dismutase-deficient fetal fibroblasts. Arch Biochem Biophys. 1997 Aug 15;344(2):424-32
  • Latest
    J:345472 Lana-Elola E, et al., Increased dosage of DYRK1A leads to congenital heart defects in a mouse model of Down syndrome. Sci Transl Med. 2024 Jan 24;16(731):eadd6883
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory