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Pbsn Gene Detail
Summary
  • Symbol
    Pbsn
  • Name
    probasin
  • Synonyms
    PB
  • Feature Type
    protein coding gene
  • IDs
    MGI:1860484
    NCBI Gene: 54192
  • Alliance
    gene page
  • Transcription Start Sites
    8 TSS
Location &
Maps
more
  • Sequence Map
    ChrX:76881504-76897106 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome X, 38.32 cM, cytoband A7.1
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    284 from dbSNP Build 142
  • Strain Annotations
    17
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1860484
 protein coding gene ChrX:76881504-76897229 (-)
129S1/SvImJ MGP_129S1SvImJ_G0035871
 protein coding gene ChrX:73667512-73684946 (-)
A/J MGP_AJ_G0035858
 protein coding gene ChrX:73958945-73973125 (-)
AKR/J MGP_AKRJ_G0035778
 protein coding gene ChrX:75871928-75891475 (-)
BALB/cJ MGP_BALBcJ_G0035838
 protein coding gene ChrX:72899731-72915717 (-)
C3H/HeJ MGP_C3HHeJ_G0035550
 protein coding gene ChrX:74163051-74178544 (-)
C57BL/6NJ MGP_C57BL6NJ_G0036370
 protein coding gene ChrX:76025159-76039014 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0033204
 protein coding gene ChrX:73238269-73250627 (-)
CAST/EiJ MGP_CASTEiJ_G0034839
 protein coding gene ChrX:59420514-59438204 (-)
CBA/J MGP_CBAJ_G0035523
 protein coding gene ChrX:78043466-78064504 (-)
DBA/2J MGP_DBA2J_G0035680
 protein coding gene ChrX:73382062-73396172 (-)
FVB/NJ MGP_FVBNJ_G0035621
 protein coding gene ChrX:72645618-72659989 (-)
LP/J MGP_LPJ_G0035766
 protein coding gene ChrX:74555992-74574097 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0035656
 protein coding gene ChrX:80785768-80804286 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0036395
 protein coding gene ChrX:73523234-73535310 (-)
PWK/PhJ MGP_PWKPhJ_G0034535
 protein coding gene ChrX:57483098-57503506 (-)
SPRET/EiJ no annotation
WSB/EiJ MGP_WSBEiJ_G0034975
 protein coding gene ChrX:72715700-72730072 (-)



Homology
less
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    7 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    4
  • GO References
    3
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    709
  • Tissues
    3
  • cDNA Data
    2
  • Literature Summary
    3
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 54192 NCBI Gene Model | MGI Sequence Detail 15603 C57BL/6J ±  kb
    transcript NM_017471 RefSeq | MGI Sequence Detail 808 C57BL/6  
    polypeptide O08976 UniProt | EBI | MGI Sequence Detail 174 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 3
      cDNA 2
      Primer pair 1

      Microarray probesets 3
    References
    more
    • Summaries
      All 29
      Developmental Gene Expression 3
      Gene Ontology 3
      Phenotypes 7
    • Earliest
      J:62973 Johnson MA, et al., Isolation and characterization of mouse probasin: An androgen-regulated protein specifically expressed in the differentiated prostate. Prostate. 2000 Jun 1;43(4):255-62
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    08/02/2024
    MGI 6.24     		The Jackson Laboratory