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Zfp276 Gene Detail
Summary
  • Symbol
    Zfp276
  • Name
    zinc finger protein (C2H2 type) 276
  • Synonyms
    D8Ertd370e, D8Ertd377e
  • Feature Type
    protein coding gene
  • IDs
    MGI:1888495
    NCBI Gene: 57247
  • Alliance
    gene page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr8:123980934-123996484 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 8, 72.09 cM
  • Mapping Data
    5 experiments
Strain
Comparison
more
  • SNPs within 2kb
    451 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1888495
 protein coding gene Chr8:123980934-123997290 (+)
129S1/SvImJ MGP_129S1SvImJ_G0034250
 protein coding gene Chr8:126857370-126872947 (+)
A/J MGP_AJ_G0034230
 protein coding gene Chr8:121602372-121618997 (+)
AKR/J MGP_AKRJ_G0034157
 protein coding gene Chr8:125131225-125149234 (+)
BALB/cJ MGP_BALBcJ_G0034223
 protein coding gene Chr8:121810689-121826320 (+)
C3H/HeJ MGP_C3HHeJ_G0033934
 protein coding gene Chr8:125834947-125851301 (+)
C57BL/6NJ MGP_C57BL6NJ_G0034743
 protein coding gene Chr8:131103034-131119532 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0031685
 protein coding gene Chr8:114420621-114435926 (+)
CAST/EiJ MGP_CASTEiJ_G0033262
 protein coding gene Chr8:125915257-125946735 (+)
CBA/J MGP_CBAJ_G0033907
 protein coding gene Chr8:135918156-135933485 (+)
DBA/2J MGP_DBA2J_G0034063
 protein coding gene Chr8:120780026-120795837 (+)
FVB/NJ MGP_FVBNJ_G0034007
 protein coding gene Chr8:119946420-119961907 (+)
LP/J MGP_LPJ_G0034153
 protein coding gene Chr8:126988448-127006893 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0034054
 protein coding gene Chr8:138052257-138075685 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0034762
 protein coding gene Chr8:125348303-125364046 (+)
PWK/PhJ MGP_PWKPhJ_G0032963
 protein coding gene Chr8:120610500-120626720 (+)
SPRET/EiJ MGP_SPRETEiJ_G0032803
 protein coding gene Chr8:124065083-124080152 (+)
WSB/EiJ MGP_WSBEiJ_G0033378
 protein coding gene Chr8:126084728-126100905 (+)



Homology
more
  • Human Ortholog
    ZNF276, zinc finger protein 276
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ZNF276, zinc finger protein 276
  • Synonyms
    CENP-Z, CENPZ, ZADT, ZFP276, ZNF477
  • Links
    NCBI Gene ID: 92822
    neXtProt AC: NX_Q8N554
    UniProt: Q8N554

  • Chr Location
    16q24.3; chr16:89720368-89740925 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotypes from 2 alleles in 2 genetic backgrounds
    4 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    10
  • GO References
    6
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    792
  • Tissues
    73
  • cDNA Data
    17
  • Literature Summary
    5
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000001065 Ensembl Gene Model | MGI Sequence Detail 15551 C57BL/6J ±  kb
transcript ENSMUST00000001092 Ensembl | MGI Sequence Detail 4071 Not Applicable  
polypeptide ENSMUSP00000001092 Ensembl | MGI Sequence Detail 614 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 24
    Genomic 1
    cDNA 19
    Primer pair 4

    Microarray probesets 6
Other
Accession IDs
less
MGI:1196248, MGI:1196409, MGI:2142748
References
more
  • Summaries
    All 35
    Developmental Gene Expression 5
    Gene Ontology 6
    Phenotypes 4
  • Earliest
    J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
  • Latest
    J:324574 Aberle T, et al., Transcription factor Zfp276 drives oligodendroglial differentiation and myelination by switching off the progenitor cell program. Nucleic Acids Res. 2022 Feb 28;50(4):1951-1968
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory