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Cdc42se1 Gene Detail
Summary
  • Symbol
    Cdc42se1
  • Name
    CDC42 small effector 1
  • Synonyms
    1300002M12Rik, SCIP1, Spec1
  • Feature Type
    protein coding gene
  • IDs
    MGI:1889510
    NCBI Gene: 57912
  • Alliance
    gene page
  • Transcription Start Sites
    10 TSS
Location &
Maps
more
  • Sequence Map
    Chr3:95136043-95143720 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 3, 40.74 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    182 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1889510
 protein coding gene Chr3:95135735-95143735 (+)
129S1/SvImJ MGP_129S1SvImJ_G0027576
 protein coding gene Chr3:95935112-95943947 (+)
A/J MGP_AJ_G0027535
 protein coding gene Chr3:92970748-92978449 (+)
AKR/J MGP_AKRJ_G0027502
 protein coding gene Chr3:95116848-95124560 (+)
BALB/cJ MGP_BALBcJ_G0027547
 protein coding gene Chr3:92748528-92756436 (+)
C3H/HeJ MGP_C3HHeJ_G0027280
 protein coding gene Chr3:95402867-95410793 (+)
C57BL/6NJ MGP_C57BL6NJ_G0027995
 protein coding gene Chr3:99502596-99510284 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0025335
 protein coding gene Chr3:89332303-89340276 (+)
CAST/EiJ MGP_CASTEiJ_G0026730
 protein coding gene Chr3:94684296-94694157 (+)
CBA/J MGP_CBAJ_G0027257
 protein coding gene Chr3:103108521-103116177 (+)
DBA/2J MGP_DBA2J_G0027396
 protein coding gene Chr3:92262316-92270718 (+)
FVB/NJ MGP_FVBNJ_G0027367
 protein coding gene Chr3:90335019-90345930 (+)
LP/J MGP_LPJ_G0027505
 protein coding gene Chr3:97239968-97249471 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0027394
 protein coding gene Chr3:109227235-109234932 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0028049
 protein coding gene Chr3:94773236-94781751 (+)
PWK/PhJ MGP_PWKPhJ_G0026458
 protein coding gene Chr3:92140515-92149253 (+)
SPRET/EiJ MGP_SPRETEiJ_G0026279
 protein coding gene Chr3:93067469-93075198 (+)
WSB/EiJ MGP_WSBEiJ_G0026812
 protein coding gene Chr3:95157909-95165611 (+)



Homology
more
  • Human Ortholog
    CDC42SE1, CDC42 small effector 1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CDC42SE1, CDC42 small effector 1
  • Synonyms
    SCIP1, SPEC1
  • Links
    NCBI Gene ID: 56882
    neXtProt AC: NX_Q9NRR8
    UniProt: Q9NRR8

  • Chr Location
    1q21.3; chr1:151050971-151070325 (-)  GRCh38
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    12 phenotype references
  • All Mutations and Alleles
    72
  • Chemically induced (other)
    1
  • Gene trapped
    67
  • Radiation induced
    1
  • Targeted
    3
  • Genomic Mutations
    2 involving Cdc42se1
  • Incidental Mutations
    APF
  • Find Mice (IMSR)
    28 strains or lines available
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    12
  • GO References
    8
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    708
  • Tissues
    2
  • cDNA Data
    9
  • Literature Summary
    4
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000046722 Ensembl Gene Model | MGI Sequence Detail 7678 C57BL/6J ±  kb
transcript ENSMUST00000053872 Ensembl | MGI Sequence Detail 2805 Not Applicable  
polypeptide ENSMUSP00000052986 Ensembl | MGI Sequence Detail 80 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 10
    cDNA 10

    Microarray probesets 4
Other
Accession IDs
less
MGI:1914138, MGI:2140011
References
more
  • Summaries
    All 42
    Developmental Gene Expression 4
    Diseases 1
    Gene Ontology 8
    Phenotypes 12
  • Earliest
    J:63564 Papanikolaou A, et al., Sequential and morphological analyses of aberrant crypt foci formation in mice of differing susceptibility to azoxymethane-induced colon carcinogenesis. Carcinogenesis. 2000 Aug;21(8):1567-72
  • Latest
    J:313619 Bedogni F, et al., Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development. Front Mol Neurosci. 2021;14:686034
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory