Tg(Wnt1)1Hev
Transgene Detail

Summary

• Symbol: Tg(Wnt1)1Hev
• Name: transgene insertion 1, Harold E Varmus
• MGI ID: MGI:1890080
• Synonyms: line 303, MMTV-wnt, MMTV-Wnt-1, MMTV-Wnt1, Wnt-1
• Transgene: Tg(Wnt1)1Hev Location: unknown
• Alliance: Tg(Wnt1)1Hev page

Transgene origin

• Strain of Origin: C57BL/6 x SJL

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(Wnt1)1Hev expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Wnt1 (MGI:98953)

• Mutation details: Wnt1 is driven by the mouse mammary tumor virus (MMTV). The construct resembles alleles found in virus-induced tumors. (J:28473)

Disease models

Expression

In Structures Affected by this Mutation:

4 anatomical structure(s)

Tumor Data

List all tumor models in MMHCdb carrying Tg(Wnt1)1Hev

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available

References

• Original: J:28473 Tsukamoto AS, et al., Expression of the int-1 gene in transgenic mice is associated with mammary gland hyperplasia and adenocarcinomas in male and female mice. Cell. 1988 Nov 18;55(4):619-25
• All: 112 reference(s)