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Spgl Gene Detail
Summary
  • Symbol
    Spgl
  • Name
    spag luxate
  • Synonyms
    Gena203
  • Feature Type
    heritable phenotypic marker
  • IDs
    MGI:1890620
  • Alliance
    gene page
Location &
Maps
less
  • Sequence Map
    Genome coordinates not available from the current reference assembly.
  • Genetic Map
    Chromosome 15, Syntenic
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotypes from 1 allele in 3 genetic backgrounds
    2 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice heterozygous for an ENU-induced mutation of this gene exhibit polydactyly of the hindlimbs. Homozygotes also exhibit forelimb polydactyly. Reduced or absent tibiae cause a rotational hindlimb defect. Craniofacial anomalies show incomplete penetrance.
References
more
  • Summaries
    All 2
    Phenotypes 2
  • Earliest
    J:205331 Hayes C, et al., Developmental Dynamics 2000 Platform and poster abstracts: Abstract P12: Identification and analysis of new limb phenotypes using ENU mutagenesis. Dev Dyn. 2000;219(Abstr P12):451
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory