Zfp108 Gene Detail

Summary

• Symbol
  Zfp108
• Name
  zinc finger protein 108

• Feature Type
  protein coding gene
• IDs
  MGI:1891198
  NCBI Gene: 54678
• Alliance
  gene page
• Transcription Start Sites
  1 TSS

Location &
Maps

• Sequence Map
  Chr7:23954219-23961870 bp, + strand

  From Ensembl annotation of GRCm39
  

• View this region in JBrowse
  

• Genome Browsers
  Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 7, 10.27 cM, cytoband A2
• Mapping Data
  2 experiments

Strain
Comparison

• SNPs within 2kb
  403 from dbSNP Build 142
• Strain Annotations
  17

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_1891198	protein coding gene	Chr7:23954142-23961870 (+)
129S1/SvImJ	MGP_129S1SvImJ_G0031820	protein coding gene	Chr7:22542424-22556690 (+)
A/J	no annotation
AKR/J	MGP_AKRJ_G0031728	protein coding gene	Chr7:22544720-22552299 (+)
BALB/cJ	MGP_BALBcJ_G0031805	protein coding gene	Chr7:22254386-22264089 (+)
C3H/HeJ	MGP_C3HHeJ_G0031526	protein coding gene	Chr7:22949478-22957059 (+)
C57BL/6NJ	MGP_C57BL6NJ_G0032269	protein coding gene	Chr7:23290814-23302109 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0029326	protein coding gene	Chr7:23521819-23529536 (+)
CAST/EiJ	MGP_CASTEiJ_G0030866	protein coding gene	Chr7:16411842-16422302 (+)
CBA/J	MGP_CBAJ_G0031490	protein coding gene	Chr7:24159481-24169402 (+)
DBA/2J	MGP_DBA2J_G0031644	protein coding gene	Chr7:21964097-21971665 (+)
FVB/NJ	MGP_FVBNJ_G0031597	protein coding gene	Chr7:21921006-21928703 (+)
LP/J	MGP_LPJ_G0031724	protein coding gene	Chr7:22907948-22916138 (+)
NOD/ShiLtJ	MGP_NODShiLtJ_G0031634	protein coding gene	Chr7:23961407-23969803 (+)
NZO/HlLtJ	MGP_NZOHlLtJ_G0032301	protein coding gene	Chr7:22254264-22262297 (+)
PWK/PhJ	MGP_PWKPhJ_G0030590	protein coding gene	Chr7:16846251-16854438 (+)
SPRET/EiJ	MGP_SPRETEiJ_G0030420	protein coding gene	Chr7:13584836-13594492 (+)
WSB/EiJ	MGP_WSBEiJ_G0030969	protein coding gene	Chr7:22372143-22379261 (+)

Homology

• Human Ortholog
  ZNF235, zinc finger protein 235

• Vertebrate Orthologs
  2

Vertebrate Orthology Source

Alliance of Genome Resources

• Human Ortholog
  ZNF235, zinc finger protein 235
  
• Synonyms
  ANF270, HZF6, ZFP93, ZNF270
• Links
  HGNC:12866

  NCBI Gene ID: 9310

  neXtProt AC: NX_Q14590

  UniProt: Q14590

  
  
• Chr Location
  19q13.31; chr19:44228729-44305046 (-)  GRCh38

---

• MGI Vertebrate Homology
  Zfp108 stringent orthology
  1 human;1 mouse;1 rat
  
• HCOP
  vertebrate homology predictions: ZNF235
• Gene Tree
  Zfp108
  

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  1 phenotype reference
  

• All Mutations and Alleles
  4
• Targeted
  4
• Incidental Mutations
  Mutagenetix , APF
• Find Mice (IMSR)
  36 strains or lines available

Expression

• Assay Results
  778
• Tissues
  51
• cDNA Data
  9
• Literature Summary
  3

Images

Tissue x Stage Matrix

• Other Mouse Links
  GEO
  Expression Atlas

Sequences &
Gene Models

• All Sequences
  42
• RefSeq
  8
• UniProt
  4
• CCDS
  CCDS85236.1

• Ensembl
  ENSMUSG00000030486 (Evidence)
• NCBI Gene
  54678

Representative Sequences			Length	Strain/Species
genomic	ENSMUSG00000030486	Ensembl Gene Model | MGI Sequence Detail	7652	C57BL/6J
transcript	ENSMUST00000205982	Ensembl | MGI Sequence Detail	2577	Not Applicable
polypeptide	ENSMUSP00000145844	Ensembl | MGI Sequence Detail	642	Not Applicable

Protein
Information

• UniProt
  4 Sequences
• InterPro Domains
  IPR050589 Ikaros C2H2-type zinc-finger
  IPR036051 KRAB domain superfamily
  IPR001909 Krueppel-associated box
  IPR050169 Krueppel C2H2-type zinc-finger
  IPR036236 Zinc finger C2H2 superfamily
  IPR013087 Zinc finger C2H2-type

Molecular
Reagents

• All nucleic 10

  cDNA 10

  
  

  Microarray probesets 3

References

• Summaries
  All 21

  Developmental Gene Expression 3

  Phenotypes 1
• Earliest
  J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
• Latest
  J:156017 Yokoyama S, et al., A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58. Dev Cell. 2009 Dec;17(6):836-48

TSS for Zfp108:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr64935	Chr7:23954169-23954237 (+)	-16 bp