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Ccl27b Gene Detail
Summary
  • Symbol
    Ccl27b
  • Name
    C-C motif chemokine ligand 27b
  • Synonyms
    CTACK, Scya27b
  • Feature Type
    protein coding gene
  • IDs
    MGI:1891389
    NCBI Gene: 100040048
  • Alliance
    gene page
Location &
Maps
more
  • Sequence Map
    Chr4:42655251-42655998 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 4, 22.73 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • Strain Annotations
    12
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1891389
 protein coding gene Chr4:42650563-42656008 (+)
129S1/SvImJ MGP_129S1SvImJ_G0028188
 protein coding gene Chr4:40692767-40693521 (+)
A/J MGP_AJ_G0028135
 protein coding gene Chr4:38226468-38227222 (-)
AKR/J MGP_AKRJ_G0028096
 protein coding gene Chr4:39232105-39232859 (-)
BALB/cJ MGP_BALBcJ_G0028147
 protein coding gene Chr4:38569211-38569965 (-)
C3H/HeJ MGP_C3HHeJ_G0027869
 protein coding gene Chr4:39698996-39699750 (-)
C57BL/6NJ MGP_C57BL6NJ_G0028602
 protein coding gene Chr4:42229107-42229861 (+)
CAROLI/EiJ no annotation
CAST/EiJ no annotation
CBA/J MGP_CBAJ_G0027846
 protein coding gene Chr4:42604243-42604997 (-)
DBA/2J MGP_DBA2J_G0027990
 protein coding gene Chr4:38153893-38154647 (-)
FVB/NJ MGP_FVBNJ_G0027957
 protein coding gene Chr4:37474240-37474994 (-)
LP/J MGP_LPJ_G0028102
 protein coding gene Chr4:40720837-40721591 (+)
NOD/ShiLtJ no annotation
NZO/HlLtJ no annotation
PWK/PhJ MGP_PWKPhJ_G0027049
 protein coding gene Chr4:38195723-38196477 (-)
SPRET/EiJ no annotation
WSB/EiJ no annotation



Homology
more
  • Human Ortholog
    CCL27, C-C motif chemokine ligand 27
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CCL27, C-C motif chemokine ligand 27
  • Synonyms
    ALP, CTACK, CTAK, ESKINE, ILC, PESKY, SCYA27
  • Links
    NCBI Gene ID: 10850
    neXtProt AC: NX_Q9Y4X3
    UniProt: Q9Y4X3

  • Chr Location
    9p13.3; chr9:34661880-34664048 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotypes from multigenic genotypes
    2 phenotype references
  • All Mutations and Alleles
    2
  • Chemically and radiation induced
    1
  • Endonuclease-mediated
    1
  • Genomic Mutations
    1 involving Ccl27b
  • Find Mice (IMSR)
    0 strains or lines available
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    3
  • GO References
    1
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

No experimental evidence to support Cellular Component annotation, following literature review. See J:73796.
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    732
  • Tissues
    16
  • cDNA Data
    2
  • Literature Summary
    1
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000096826 Ensembl Gene Model | MGI Sequence Detail 748 C57BL/6J ±  kb
transcript ENSMUST00000177785 Ensembl | MGI Sequence Detail 418 Not Applicable  
polypeptide ENSMUSP00000137284 Ensembl | MGI Sequence Detail 120 Not Applicable  
For the selected sequence
Molecular
Reagents
less
  • All nucleic 3
    cDNA 3
Other
Accession IDs
less
MGI:3710584
References
more
  • Summaries
    All 13
    Developmental Gene Expression 1
    Gene Ontology 1
    Phenotypes 2
  • Earliest
    J:66381 Nakano H, et al., Gene duplications at the chemokine locus on mouse chromosome 4: multiple strain-specific haplotypes and the deletion of secondary lymphoid-organ chemokine and EBI-1 ligand chemokine genes in the plt mutation. J Immunol. 2001 Jan 1;166(1):361-9
  • Latest
    J:330550 Davila ML, et al., CCL27 is a crucial regulator of immune homeostasis of the skin and mucosal tissues. iScience. 2022 Jun 17;25(6):104426
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory