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Igsf6 Gene Detail
Summary
  • Symbol
    Igsf6
  • Name
    immunoglobulin superfamily, member 6
  • Feature Type
    protein coding gene
  • IDs
    MGI:1891393
    NCBI Gene: 80719
  • Alliance
    genome feature page
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:120663290-120673753 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 7, 65.07 cM, cytoband F2-F3
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    285 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1891393
 protein coding gene Chr7:120663290-120673795 (-)
129S1/SvImJ ENSMUSG00200021872
 protein coding gene Chr7:107183987-107194494 (-)
A/J ENSMUSG00195034386
 protein coding gene Chr7:111714410-111724909 (-)
AKR/J ENSMUSG00220019247
 protein coding gene Chr7:105144776-105155281 (-)
BALB/cJ ENSMUSG00180031711
 protein coding gene Chr7:108375663-108386169 (-)
C3H/HeJ ENSMUSG00175025137
 protein coding gene Chr7:109089030-109099535 (-)
C57BL/6NJ ENSMUSG00215015719
 protein coding gene Chr7:108339082-108349588 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0030406
 protein coding gene Chr7:123191592-123201696 (-)
CAST/EiJ ENSTCUG00005038044
 protein coding gene Chr7:111648566-111659419 (-)
CBA/J ENSMUSG00210023977
 protein coding gene Chr7:108816808-108827313 (-)
DBA/2J ENSMUSG00185048225
 protein coding gene Chr7:113162805-113173310 (-)
FVB/NJ ENSMUSG00205023228
 protein coding gene Chr7:108823050-108833555 (-)
JF1/MsJ ENSUMUG00000026252
 protein coding gene Chr7:118251308-118262362 (-)
LP/J ENSMUSG00230033275
 protein coding gene Chr7:119271884-119282389 (-)
NOD/ShiLtJ ENSMUSG00190019098
 protein coding gene Chr7:109015342-109025847 (-)
NZO/HlLtJ ENSMUSG00225038051
 protein coding gene Chr7:117520776-117531281 (-)
PWK/PhJ ENSLUMG00010012076
 protein coding gene Chr7:107356358-107366863 (-)
SPRET/EiJ ENSMSPG00010008223
 protein coding gene Chr7:108567931-108578245 (-)
WSB/EiJ ENSIUOG00005012082
 protein coding gene Chr7:109701744-109712257 (-)



Homology
more
  • Human Ortholog
    IGSF6, immunoglobulin superfamily member 6
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    IGSF6, immunoglobulin superfamily member 6
  • Synonyms
    DORA
  • Links
    NCBI Gene ID: 10261
    UniProt: O95976

  • Chr Location
    16p12.2; chr16:21639550-21652611 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    1
  • GO References
    1
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    597
  • cDNA Data
    12
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 80719 NCBI Gene Model | MGI Sequence Detail 10464 C57BL/6J ±  kb
transcript NM_030691 RefSeq | MGI Sequence Detail 2133 129P2/Ola  
polypeptide P0C6B7 UniProt | EBI | MGI Sequence Detail 237 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 13
    Genomic 1
    cDNA 12

    Microarray probesets 3
References
more
  • Summaries
    All 27
    Gene Ontology 1
    Phenotypes 7
  • Earliest
    J:67662 Bates EE, et al., The mouse and human IGSF6 (DORA) genes map to the inflammatory bowel disease 1 locus and are embedded in an intron of a gene of unknown function. Immunogenetics. 2000 Nov;52(1-2):112-20
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/01/2026
MGI 6.24 		The Jackson Laboratory