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Igsf6 Gene Detail
Summary
  • Symbol
    Igsf6
  • Name
    immunoglobulin superfamily, member 6
  • Feature Type
    protein coding gene
  • IDs
    MGI:1891393
    NCBI Gene: 80719
  • Alliance
    gene page
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:120663290-120673753 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 7, 65.07 cM, cytoband F2-F3
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    285 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1891393
 protein coding gene Chr7:120663290-120673795 (-)
129S1/SvImJ MGP_129S1SvImJ_G0032940
 protein coding gene Chr7:125083345-125094676 (-)
A/J MGP_AJ_G0032923
 protein coding gene Chr7:121819650-121830102 (-)
AKR/J MGP_AKRJ_G0032855
 protein coding gene Chr7:124944283-124954746 (-)
BALB/cJ MGP_BALBcJ_G0032928
 protein coding gene Chr7:121537149-121547923 (-)
C3H/HeJ MGP_C3HHeJ_G0032638
 protein coding gene Chr7:124860274-124870714 (-)
C57BL/6NJ MGP_C57BL6NJ_G0033434
 protein coding gene Chr7:130029788-130040355 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0030406
 protein coding gene Chr7:123191592-123201696 (-)
CAST/EiJ MGP_CASTEiJ_G0031966
 protein coding gene Chr7:116622709-116633289 (-)
CBA/J MGP_CBAJ_G0032611
 protein coding gene Chr7:134359023-134372166 (-)
DBA/2J MGP_DBA2J_G0032763
 protein coding gene Chr7:119853054-119863517 (-)
FVB/NJ MGP_FVBNJ_G0032716
 protein coding gene Chr7:119711919-119722382 (-)
LP/J MGP_LPJ_G0032857
 protein coding gene Chr7:126524485-126534977 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0032748
 protein coding gene Chr7:135824058-135835394 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0033454
 protein coding gene Chr7:123938000-123949053 (-)
PWK/PhJ MGP_PWKPhJ_G0031674
 protein coding gene Chr7:112782177-112792658 (-)
SPRET/EiJ MGP_SPRETEiJ_G0031520
 protein coding gene Chr7:110699075-110709347 (-)
WSB/EiJ MGP_WSBEiJ_G0032079
 protein coding gene Chr7:124863739-124874202 (-)



Homology
more
  • Human Ortholog
    IGSF6, immunoglobulin superfamily member 6
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    IGSF6, immunoglobulin superfamily member 6
  • Synonyms
    DORA
  • Links
    NCBI Gene ID: 10261
    neXtProt AC: NX_O95976
    UniProt: O95976

  • Chr Location
    16p12.2; chr16:21639550-21652608 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    1
  • GO References
    1
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    12
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 80719 NCBI Gene Model | MGI Sequence Detail 10464 C57BL/6J ±  kb
transcript NM_030691 RefSeq | MGI Sequence Detail 2133 129P2/Ola  
polypeptide P0C6B7 UniProt | EBI | MGI Sequence Detail 237 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 13
    Genomic 1
    cDNA 12

    Microarray probesets 3
References
more
  • Summaries
    All 24
    Gene Ontology 1
    Phenotypes 5
  • Earliest
    J:67662 Bates EE, et al., The mouse and human IGSF6 (DORA) genes map to the inflammatory bowel disease 1 locus and are embedded in an intron of a gene of unknown function. Immunogenetics. 2000 Nov;52(1-2):112-20
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory