BY367451 Gene Detail

Summary

• Symbol
  BY367451
• Name
  cDNA sequence, BY367451
• Synonyms
  Atxn8os, Klhl1as, Sca8

• Feature Type
  unclassified non-coding RNA gene
• IDs
  MGI:1891412
  NCBI Gene: 108639
• Alliance
  gene page

Location &
Maps

• Sequence Map
  Chr14:96794007-96794446 bp

  From MGI annotation of GRCm39
  

• View this region in JBrowse
  

• Genome Browsers
  Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 14, Syntenic

Strain
Comparison

• SNPs within 2kb
  158 from dbSNP Build 142
• Strain Annotations
  1

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_1891412	unclassified non-coding RNA gene	Chr14:96794007-96794446 (.)
129S1/SvImJ	no annotation
A/J	no annotation
AKR/J	no annotation
BALB/cJ	no annotation
C3H/HeJ	no annotation
C57BL/6NJ	no annotation
CAROLI/EiJ	no annotation
CAST/EiJ	no annotation
CBA/J	no annotation
DBA/2J	no annotation
FVB/NJ	no annotation
LP/J	no annotation
NOD/ShiLtJ	no annotation
NZO/HlLtJ	no annotation
PWK/PhJ	no annotation
SPRET/EiJ	no annotation
WSB/EiJ	no annotation

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  3 phenotypes from 2 alleles in 1 genetic background
  3 phenotype references
  

• All Mutations and Alleles
  3
• Chemically induced (other)
  1
• Targeted
  2
• Genomic Mutations
  1 involving BY367451
• Find Mice (IMSR)
  0 strains or lines available

Mice both homozygous and heterozygous for disruption of this gene develop abnormalities in gait and defects in motor coordination with time. Dendritic atrophy of Purkinje cells is also seen.

Gene Ontology
(GO)
Classifications

• All GO Annotations
  1
• GO References
  1

Expression

• cDNA Data
  1

Sequences &
Gene Models

• All Sequences
  2

• NCBI Gene
  108639

Representative Sequences			Length	Strain/Species
transcript	BY367451	GenBank | ENA | DDBJ | MGI Sequence Detail	440	C57BL/6J

Molecular
Reagents

• All nucleic 1

  cDNA 1

References

• Summaries
  All 10

  Gene Ontology 1

  Phenotypes 3
• Earliest
  J:62929 Nemes JP, et al., The SCA8 transcript is an antisense RNA to a brain-specific transcript encoding a novel actin-binding protein (KLHL1). Hum Mol Genet. 2000 Jun 12;9(10):1543-51
• Latest
  J:140562 Chen WL, et al., SCA8 mRNA expression suggests an antisense regulation of KLHL1 and correlates to SCA8 pathology. Brain Res. 2008 Oct 3;1233:176-84