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Wrap73 Gene Detail
Summary
  • Symbol
    Wrap73
  • Name
    WD repeat containing, antisense to Trp73
  • Synonyms
    2610044M17Rik, 5330425N03Rik, DD57, Wdr8
  • Feature Type
    protein coding gene
  • IDs
    MGI:1891749
    NCBI Gene: 59002
  • Alliance
    gene page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr4:154226811-154241278 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 4, 83.86 cM, cytoband E2
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    540 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1891749
 protein coding gene Chr4:154226811-154251877 (+)
129S1/SvImJ MGP_129S1SvImJ_G0029192
 protein coding gene Chr4:158390728-158420843 (+)
A/J MGP_AJ_G0029157
 protein coding gene Chr4:151746369-151771314 (+)
AKR/J MGP_AKRJ_G0029105
 protein coding gene Chr4:155887756-155915080 (+)
BALB/cJ MGP_BALBcJ_G0029173
 protein coding gene Chr4:152213106-152240293 (+)
C3H/HeJ MGP_C3HHeJ_G0028894
 protein coding gene Chr4:156420324-156450342 (+)
C57BL/6NJ MGP_C57BL6NJ_G0029622
 protein coding gene Chr4:164057137-164084587 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0026868
 protein coding gene Chr4:144044340-144074121 (+)
CAST/EiJ MGP_CASTEiJ_G0028307
 protein coding gene Chr4:153819868-153848992 (+)
CBA/J MGP_CBAJ_G0028856
 protein coding gene Chr4:168980789-169012088 (+)
DBA/2J MGP_DBA2J_G0029005
 protein coding gene Chr4:151773100-151797777 (+)
FVB/NJ MGP_FVBNJ_G0028969
 protein coding gene Chr4:150975957-151000768 (+)
LP/J MGP_LPJ_G0029095
 protein coding gene Chr4:158300933-158330121 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0028996
 protein coding gene Chr4:171896640-171927338 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0029654
 protein coding gene Chr4:156451413-156477039 (+)
PWK/PhJ MGP_PWKPhJ_G0028027
 protein coding gene Chr4:147855677-147881382 (+)
SPRET/EiJ MGP_SPRETEiJ_G0027861
 protein coding gene Chr4:150744004-150776233 (+)
WSB/EiJ MGP_WSBEiJ_G0028387
 protein coding gene Chr4:156617863-156647789 (+)



Homology
more
  • Human Ortholog
    WRAP73, WD repeat containing, antisense to TP73
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    WRAP73, WD repeat containing, antisense to TP73
  • Synonyms
    WDR8
  • Links
    NCBI Gene ID: 49856
    neXtProt AC: NX_Q9P2S5
    UniProt: Q9P2S5

  • Chr Location
    1p36.32; chr1:3630767-3652761 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    14
  • GO References
    7
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    724
  • Tissues
    2
  • cDNA Data
    31
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 59002 NCBI Gene Model | MGI Sequence Detail 14468 C57BL/6J ±  kb
transcript NM_021499 RefSeq | MGI Sequence Detail 1600 C57BL/6  
polypeptide Q9JM98 UniProt | EBI | MGI Sequence Detail 462 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    3 Sequences
  • Protein Ontology
    PR:000029874 WD repeat-containing protein WRAP73
    (term hierarchy)
  • InterPro Domains
    IPR052778 Centrosome-associated WD domain-containing protein
    IPR011044 Quinoprotein amine dehydrogenase, beta chain-like
    IPR001680 WD40 repeat
    IPR036322 WD40-repeat-containing domain superfamily
    IPR015943 WD40/YVTN repeat-like-containing domain superfamily
Molecular
Reagents
less
  • All nucleic 32
    cDNA 32

    Microarray probesets 3
Other
Accession IDs
less
MGI:1913832, MGI:1924405
References
more
  • Summaries
    All 38
    Developmental Gene Expression 1
    Gene Ontology 7
    Phenotypes 7
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:233615 Kurtulmus B, et al., WDR8 is a centriolar satellite and centriole-associated protein that promotes ciliary vesicle docking during ciliogenesis. J Cell Sci. 2016 Feb 1;129(3):621-36
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory