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Dtd1 Gene Detail
Summary
  • Symbol
    Dtd1
  • Name
    D-tyrosyl-tRNA deacylase 1
  • Synonyms
    0610006H08Rik, Hars2
  • Feature Type
    protein coding gene
  • IDs
    MGI:1913294
    NCBI Gene: 66044
  • Alliance
    gene page
  • Transcription Start Sites
    9 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:144441873-144610667 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 2, 71.02 cM, cytoband H1
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    3713 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1913294
 protein coding gene Chr2:144441817-144610678 (+)
129S1/SvImJ MGP_129S1SvImJ_G0026591
 protein coding gene Chr2:148709144-148881563 (+)
A/J MGP_AJ_G0026555
 protein coding gene Chr2:142688663-142858100 (+)
AKR/J MGP_AKRJ_G0026529
 protein coding gene Chr2:146781384-146958140 (+)
BALB/cJ MGP_BALBcJ_G0026567
 protein coding gene Chr2:143125542-143294468 (+)
C3H/HeJ MGP_C3HHeJ_G0026310
 protein coding gene Chr2:147327772-147504222 (+)
C57BL/6NJ MGP_C57BL6NJ_G0027012
 protein coding gene Chr2:153155380-153330251 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0024389
 protein coding gene Chr2:136861409-137020868 (+)
CAST/EiJ MGP_CASTEiJ_G0025771
 protein coding gene Chr2:147664099-147834536 (+)
CBA/J MGP_CBAJ_G0026290
 protein coding gene Chr2:158746889-158928393 (+)
DBA/2J MGP_DBA2J_G0026424
 protein coding gene Chr2:141967419-142129742 (+)
FVB/NJ MGP_FVBNJ_G0026388
 protein coding gene Chr2:140547657-140708665 (+)
LP/J MGP_LPJ_G0026528
 protein coding gene Chr2:148855910-149030233 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0026408
 protein coding gene Chr2:162939621-163123513 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0027067
 protein coding gene Chr2:146772251-146951323 (+)
PWK/PhJ MGP_PWKPhJ_G0025507
 protein coding gene Chr2:141630731-141794397 (+)
SPRET/EiJ MGP_SPRETEiJ_G0025308
 protein coding gene Chr2:145819473-145988938 (+)
WSB/EiJ MGP_WSBEiJ_G0025844
 protein coding gene Chr2:147787501-147960536 (+)



Homology
more
  • Human Ortholog
    DTD1, D-aminoacyl-tRNA deacylase 1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    DTD1, D-aminoacyl-tRNA deacylase 1
  • Synonyms
    C20orf88, DTD, DUE-B, DUEB, HARS2, pqn-68
  • Links
    NCBI Gene ID: 92675
    neXtProt AC: NX_Q8TEA8
    UniProt: Q8TEA8

  • Chr Location
    20p11.23; chr20:18587942-18766644 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    9 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    14
  • GO References
    6
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    800
  • Tissues
    94
  • cDNA Data
    49
  • Literature Summary
    2
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 66044 NCBI Gene Model | MGI Sequence Detail 168795 C57BL/6J ±  kb
transcript NM_025314 RefSeq | MGI Sequence Detail 1283 C57BL/6  
polypeptide Q9DD18 UniProt | EBI | MGI Sequence Detail 209 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 49
    cDNA 49

    Microarray probesets 3
References
more
  • Summaries
    All 35
    Developmental Gene Expression 2
    Gene Ontology 6
    Phenotypes 9
  • Earliest
    J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
  • Latest
    J:198011 Eom T, et al., NOVA-dependent regulation of cryptic NMD exons controls synaptic protein levels after seizure. Elife. 2013;2:e00178
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory