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Cndp2 Gene Detail
Summary
  • Symbol
    Cndp2
  • Name
    CNDP dipeptidase 2
  • Synonyms
    0610010E05Rik, Cn2, Dip-2, Pep-1, Pep1
  • Feature Type
    protein coding gene
  • IDs
    MGI:1913304
    NCBI Gene: 66054
  • Alliance
    gene page
  • Transcription Start Sites
    8 TSS
Location &
Maps
more
  • Sequence Map
    Chr18:84685590-84703827 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 18, 57.53 cM, cytoband E3
  • Mapping Data
    6 experiments
Strain
Comparison
more
  • SNPs within 2kb
    558 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1913304
 protein coding gene Chr18:84685590-84703827 (-)
129S1/SvImJ MGP_129S1SvImJ_G0024608
 protein coding gene Chr18:85827626-85846705 (-)
A/J MGP_AJ_G0024575
 protein coding gene Chr18:82058195-82076917 (-)
AKR/J MGP_AKRJ_G0024546
 protein coding gene Chr18:84500777-84522883 (-)
BALB/cJ MGP_BALBcJ_G0024573
 protein coding gene Chr18:82253013-82271346 (-)
C3H/HeJ MGP_C3HHeJ_G0024342
 protein coding gene Chr18:84605074-84623168 (-)
C57BL/6NJ MGP_C57BL6NJ_G0025020
 protein coding gene Chr18:87965511-87982976 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0022451
 protein coding gene Chr18:80754975-80771914 (-)
CAST/EiJ MGP_CASTEiJ_G0023815
 protein coding gene Chr18:84972320-84992256 (-)
CBA/J MGP_CBAJ_G0024312
 protein coding gene Chr18:91118898-91151040 (-)
DBA/2J MGP_DBA2J_G0026040
 protein coding gene Chr2:100707892-100713286 (-)
FVB/NJ MGP_FVBNJ_G0024408
 protein coding gene Chr18:80913487-80931099 (-)
LP/J MGP_LPJ_G0024526
 protein coding gene Chr18:85630158-85648891 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0024438
 protein coding gene Chr18:92353776-92376388 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0025069
 protein coding gene Chr18:84710234-84728667 (-)
PWK/PhJ MGP_PWKPhJ_G0023560
 protein coding gene Chr18:81974676-81992169 (-)
SPRET/EiJ MGP_SPRETEiJ_G0023366
 protein coding gene Chr18:84746612-84765413 (-)
WSB/EiJ MGP_WSBEiJ_G0023877
 protein coding gene Chr18:84667743-84685105 (-)



Homology
more
  • Human Ortholog
    CNDP2, carnosine dipeptidase 2
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CNDP2, carnosine dipeptidase 2
  • Synonyms
    CN2, CPGL, HEL-S-13, HsT2298, PEPA
  • Links
    NCBI Gene ID: 55748
    neXtProt AC: NX_Q96KP4
    UniProt: Q96KP4

  • Chr Location
    18q22.3; chr18:74495816-74523454 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    10 phenotypes from 1 allele in 1 genetic background
    14 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    15
  • GO References
    14
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    804
  • Tissues
    98
  • cDNA Data
    230
  • Literature Summary
    2
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 66054 NCBI Gene Model | MGI Sequence Detail 18238 C57BL/6J ±  kb
    transcript NM_001289531 RefSeq | MGI Sequence Detail 2169 C57BL/6  
    polypeptide Q9D1A2 UniProt | EBI | MGI Sequence Detail 475 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 231
      cDNA 230
      Other 1

      Microarray probesets 4
    Other
    Accession IDs
    less
    MGD-MRK-13231, MGD-MRK-13236, MGD-MRK-8851, MGI:2147396, MGI:97539
    References
    more
    • Summaries
      All 56
      Developmental Gene Expression 2
      Gene Ontology 14
      Phenotypes 14
    • Earliest
      J:5133 Lewis WH, et al., Electrophoretic heterogeneity of mouse erythrocyte peptidases. Biochem Genet. 1969 Oct;3(5):493-8
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    Send questions and comments to User Support.     		last database update
    12/10/2024
    MGI 6.24     		The Jackson Laboratory