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Uqcr10 Gene Detail
Summary
  • Symbol
    Uqcr10
  • Name
    ubiquinol-cytochrome c reductase, complex III subunit X
  • Synonyms
    1110020P15Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1913402
    NCBI Gene: 66152
  • Alliance
    gene page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:4651973-4654342 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 11, 2.96 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    162 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1913402
 protein coding gene Chr11:4651968-4654344 (-)
129S1/SvImJ MGP_129S1SvImJ_G0017986
 protein coding gene Chr11:1678749-1681156 (-)
A/J MGP_AJ_G0017959
 protein coding gene Chr11:1649681-1652040 (-)
AKR/J MGP_AKRJ_G0017923
 protein coding gene Chr11:1720859-1723218 (-)
BALB/cJ MGP_BALBcJ_G0017927
 protein coding gene Chr11:1626885-1629244 (-)
C3H/HeJ MGP_C3HHeJ_G0017740
 protein coding gene Chr11:1614108-1618186 (-)
C57BL/6NJ MGP_C57BL6NJ_G0018379
 protein coding gene Chr11:1747689-1750058 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0016037
 protein coding gene Chr11:1543636-1546357 (-)
CAST/EiJ MGP_CASTEiJ_G0017302
 protein coding gene Chr11:1588006-1590366 (-)
CBA/J MGP_CBAJ_G0017715
 protein coding gene Chr11:2019217-2021600 (-)
DBA/2J MGP_DBA2J_G0017825
 protein coding gene Chr11:1554070-1556432 (-)
FVB/NJ MGP_FVBNJ_G0017817
 protein coding gene Chr11:1592735-1595088 (-)
LP/J MGP_LPJ_G0017896
 protein coding gene Chr11:1770153-1772503 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0017843
 protein coding gene Chr11:1688025-1690384 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0018419
 protein coding gene Chr11:1727407-1730977 (-)
PWK/PhJ MGP_PWKPhJ_G0017082
 protein coding gene Chr11:1562608-1565088 (-)
SPRET/EiJ MGP_SPRETEiJ_G0016879
 protein coding gene Chr11:1697842-1701409 (-)
WSB/EiJ MGP_WSBEiJ_G0017356
 protein coding gene Chr11:1603414-1605764 (-)



Homology
more
  • Human Ortholog
    UQCR10, ubiquinol-cytochrome c reductase, complex III subunit X
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    UQCR10, ubiquinol-cytochrome c reductase, complex III subunit X
  • Synonyms
    HSPC051, HSPC119, HSPC151, QCR9, UCCR7.2, UCRC
  • Links
    NCBI Gene ID: 29796
    neXtProt AC: NX_Q9UDW1
    UniProt: Q9UDW1

  • Chr Location
    22q12.2; chr22:29767369-29770413 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotypes from 2 alleles in 2 genetic backgrounds
    1 images
    12 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a knock-out allele show embryonic growth retardation, small egg cylinders, disorganized extraembryonic tissue, failure of primitive streak formation and gastrulation, and complete embryonic lethality by E9.5.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    12
  • GO References
    9
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    944
  • Tissues
    113
  • cDNA Data
    186
  • Literature Summary
    4
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000059534 Ensembl Gene Model | MGI Sequence Detail 2370 C57BL/6J ±  kb
    transcript ENSMUST00000058407 Ensembl | MGI Sequence Detail 434 Not Applicable  
    polypeptide ENSMUSP00000054856 Ensembl | MGI Sequence Detail 64 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 186
      cDNA 186

      Microarray probesets 4
    Other
    Accession IDs
    less
    MGI:2144057
    References
    more
    • Summaries
      All 43
      Developmental Gene Expression 4
      Gene Ontology 9
      Phenotypes 12
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:355679 Vercellino I, et al., SCAF1 drives the compositional diversity of mammalian respirasomes. Nat Struct Mol Biol. 2024 Jul;31(7):1061-1071
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    11/12/2024
    MGI 6.24     		The Jackson Laboratory