S100a14 MGI Mouse Gene Detail - MGI:1913416 - S100 calcium binding protein A14

Symbol

S100a14
Name

S100 calcium binding protein A14
Synonyms

1110013O05Rik, S100a15

Feature Type

protein coding gene
IDs

MGI:1913416
NCBI Gene: 66166
Alliance

gene page
Transcription Start Sites

6 TSS

Sequence Map

Chr3:90434163-90436144 bp, + strand
From Ensembl annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 3, 39.25 cM, cytoband F2
Mapping Data

4 experiments

SNPs within 2kb

88 from dbSNP Build 142
Strain Annotations

18

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_1913416	protein coding gene	Chr3:90434156-90436144 (+)
129S1/SvImJ	MGP_129S1SvImJ_G0027470	protein coding gene	Chr3:90854001-90855982 (+)
A/J	MGP_AJ_G0027434	protein coding gene	Chr3:87821944-87823925 (+)
AKR/J	MGP_AKRJ_G0027399	protein coding gene	Chr3:89981438-89983419 (+)
BALB/cJ	MGP_BALBcJ_G0027443	protein coding gene	Chr3:87775640-87777621 (+)
C3H/HeJ	MGP_C3HHeJ_G0027185	protein coding gene	Chr3:90145639-90147620 (+)
C57BL/6NJ	MGP_C57BL6NJ_G0027889	protein coding gene	Chr3:94256053-94258034 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0025242	protein coding gene	Chr3:83316711-83318717 (+)
CAST/EiJ	MGP_CASTEiJ_G0026631	protein coding gene	Chr3:90534562-90536542 (+)
CBA/J	MGP_CBAJ_G0027160	protein coding gene	Chr3:97470776-97472757 (+)
DBA/2J	MGP_DBA2J_G0027297	protein coding gene	Chr3:87185889-87187870 (+)
FVB/NJ	MGP_FVBNJ_G0027265	protein coding gene	Chr3:85519854-85521835 (+)
LP/J	MGP_LPJ_G0027406	protein coding gene	Chr3:91906171-91908152 (+)
NOD/ShiLtJ	MGP_NODShiLtJ_G0027286	protein coding gene	Chr3:103704240-103706220 (+)
NZO/HlLtJ	MGP_NZOHlLtJ_G0027948	protein coding gene	Chr3:89732328-89734309 (+)
PWK/PhJ	MGP_PWKPhJ_G0026365	protein coding gene	Chr3:87083487-87085568 (+)
SPRET/EiJ	MGP_SPRETEiJ_G0026185	protein coding gene	Chr3:88907616-88909596 (+)
WSB/EiJ	MGP_WSBEiJ_G0026713	protein coding gene	Chr3:90137119-90139100 (+)

Human Ortholog

S100A14, S100 calcium binding protein A14

Vertebrate Orthologs

3

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

S100A14, S100 calcium binding protein A14
Synonyms

BCMP84, S100A15
Links

HGNC:18901

NCBI Gene ID: 57402

neXtProt AC: NX_Q9HCY8

UniProt: Q9HCY8
Chr Location

1q21.3; chr1:153614255-153616986 (-) GRCh38

MGI Vertebrate Homology

S100a14 stringent orthology
1 human;1 mouse;2 zebrafish
HCOP

vertebrate homology predictions: S100A14
Gene Tree

S100a14

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References

1 with disease annotations

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Phenotype Summary

4 phenotypes from 1 allele in 1 genetic background
12 phenotype references

Phenotype Overview

Blue squares indicate phenotypes directly attributed to mutations/alleles of this gene.

adipose tissue	behavior/neurological	cardiovascular system	cellular	craniofacial	digestive/alimentary system	embryo	endocrine/exocrine glands	growth/size/body	hearing/vestibular/ear	hematopoietic system	homeostasis/metabolism	integument	immune system	limbs/digits/tail	liver/biliary system	mortality/aging	muscle	nervous system	pigmentation	renal/urinary system	reproductive system	respiratory system	skeleton	taste/olfaction	neoplasm	vision/eye

Click cells to view annotations.

All Mutations and Alleles

8
Chemically induced (other)

1
Endonuclease-mediated

1
Radiation induced

1
Targeted

5
Genomic Mutations

2 involving S100a14
Find Mice (IMSR)

13 strains or lines available
Comparison Matrix

Gene Expression + Phenotype

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All GO Annotations

22
GO References

4

Molecular Function

carbohydrate derivative binding	cytoskeletal protein binding	DNA binding	enzyme regulator	hydrolase	ligase	lipid binding	oxidoreductase	RNA binding	signaling receptor activity	signaling receptor binding	transcription	transferase	transporter

Biological Process

carbohydrate derivative metabolism	cell differentiation	cell population proliferation	cellular component organization	DNA-templated transcription	establishment of localization	homeostatic process	immune system process	lipid metabolic process	programmed cell death	protein metabolic process	response to stimulus	signaling	system development

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	membraneless organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	protein-containing complex	synapse	vacuole

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

761
Tissues

9
cDNA Data

27
Literature Summary

1

Images

Tissue x Stage Matrix

Comparison Matrix

Gene Expression + Phenotype

Other Mouse Links

Allen Institute

GEO

Expression Atlas

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All Sequences

43
RefSeq

6
UniProt

2
CCDS

CCDS17535.1, CCDS50971.1

Ensembl

ENSMUSG00000042306 (Evidence)
NCBI Gene

66166

			Length	Strain/Species	Flank
genomic	ENSMUSG00000042306	Ensembl Gene Model \| MGI Sequence Detail	1982	C57BL/6J	± kb
transcript	ENSMUST00000199538	Ensembl \| MGI Sequence Detail	483	Not Applicable
polypeptide	ENSMUSP00000142428	Ensembl \| MGI Sequence Detail	104	Not Applicable

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UniProt

2 Sequences
Protein Ontology

PR:000014407 protein S100-A14

(term hierarchy)
InterPro Domains

IPR011992 EF-hand domain pair

IPR013787 S100/CaBP-9k-type, calcium binding, subdomain

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All nucleic 27

cDNA 27

Microarray probesets 4

Summaries

All 42

Developmental Gene Expression 1

Diseases 1

Gene Ontology 4

Phenotypes 12
Earliest

J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
Latest

J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136

TSS for S100a14:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr30211	Chr3:90434081-90434086 (+)	-79 bp
Tssr30212	Chr3:90434132-90434139 (+)	-27 bp
Tssr30213	Chr3:90434163-90434166 (+)	2 bp
Tssr30214	Chr3:90434168-90434188 (+)	15 bp
Tssr30215	Chr3:90434449-90434483 (+)	303 bp
Tssr30216	Chr3:90435046-90435060 (+)	890 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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