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Chchd5 Gene Detail
Summary
  • Symbol
    Chchd5
  • Name
    coiled-coil-helix-coiled-coil-helix domain containing 5
  • Synonyms
    1110027L01Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1913420
    NCBI Gene: 66170
  • Alliance
    gene page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:128971620-128976032 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 2, 62.72 cM, cytoband F3
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    195 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1913420
 protein coding gene Chr2:128971620-128976054 (+)
129S1/SvImJ MGP_129S1SvImJ_G0026484
 protein coding gene Chr2:132505940-132510370 (+)
A/J MGP_AJ_G0026448
 protein coding gene Chr2:127136248-127140682 (+)
AKR/J MGP_AKRJ_G0026423
 protein coding gene Chr2:130745766-130750194 (+)
BALB/cJ MGP_BALBcJ_G0026460
 protein coding gene Chr2:127400548-127404973 (+)
C3H/HeJ MGP_C3HHeJ_G0026203
 protein coding gene Chr2:131257345-131261770 (+)
C57BL/6NJ MGP_C57BL6NJ_G0026905
 protein coding gene Chr2:136651210-136655644 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0024282
 protein coding gene Chr2:121960456-121965873 (+)
CAST/EiJ MGP_CASTEiJ_G0025664
 protein coding gene Chr2:131515229-131519651 (+)
CBA/J MGP_CBAJ_G0026183
 protein coding gene Chr2:141700889-141705314 (+)
DBA/2J MGP_DBA2J_G0026317
 protein coding gene Chr2:126525686-126530101 (+)
FVB/NJ MGP_FVBNJ_G0026281
 protein coding gene Chr2:125175977-125180408 (+)
LP/J MGP_LPJ_G0026422
 protein coding gene Chr2:132746658-132751088 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0026301
 protein coding gene Chr2:145613906-145618336 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0026960
 protein coding gene Chr2:130782141-130786571 (+)
PWK/PhJ MGP_PWKPhJ_G0025400
 protein coding gene Chr2:126102846-126107270 (+)
SPRET/EiJ MGP_SPRETEiJ_G0025202
 protein coding gene Chr2:129891919-129896546 (+)
WSB/EiJ MGP_WSBEiJ_G0025738
 protein coding gene Chr2:131700791-131705193 (+)



Homology
more
  • Human Ortholog
    CHCHD5, coiled-coil-helix-coiled-coil-helix domain containing 5
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CHCHD5, coiled-coil-helix-coiled-coil-helix domain containing 5
  • Synonyms
    C2orf9, CHTM1, MIC14, MIX14
  • Links
    NCBI Gene ID: 84269
    neXtProt AC: NX_Q9BSY4
    UniProt: Q9BSY4

  • Chr Location
    2q14.1; chr2:112584240-112589275 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    10 phenotype references
  • All Mutations and Alleles
    47
  • Chemically induced (other)
    1
  • Endonuclease-mediated
    1
  • Gene trapped
    43
  • Radiation induced
    1
  • Targeted
    1
  • Genomic Mutations
    2 involving Chchd5
  • Find Mice (IMSR)
    24 strains or lines available
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    3
  • GO References
    2
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    723
  • Tissues
    5
  • cDNA Data
    58
  • Literature Summary
    2
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 66170 NCBI Gene Model | MGI Sequence Detail 4413 C57BL/6J ±  kb
transcript NM_025395 RefSeq | MGI Sequence Detail 1313 C57BL/6  
polypeptide Q9CQP3 UniProt | EBI | MGI Sequence Detail 110 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    2 Sequences
  • Protein Ontology
    PR:000030651 coiled-coil-helix-coiled-coil-helix domain-containing protein 5
    (term hierarchy)
  • InterPro Domains
    IPR010625 CHCH
    IPR052848 Coiled-coil-helix-coiled-coil-helix domain-containing protein
    IPR031731 IMS import disulfide relay-system, CHCH-CHCH-like Cx9C
Molecular
Reagents
less
  • All nucleic 58
    cDNA 58

    Microarray probesets 5
Other
Accession IDs
less
MGI:2139271
References
more
  • Summaries
    All 33
    Developmental Gene Expression 2
    Gene Ontology 2
    Phenotypes 10
  • Earliest
    J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
  • Latest
    J:313619 Bedogni F, et al., Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development. Front Mol Neurosci. 2021;14:686034
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory