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Tmem9 Gene Detail
Summary
  • Symbol
    Tmem9
  • Name
    transmembrane protein 9
  • Synonyms
    1500015G18Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1913491
    NCBI Gene: 66241
  • Alliance
    gene page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:135935957-135962768 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 1, 59.51 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    921 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1913491
 protein coding gene Chr1:135935888-135963080 (+)
129S1/SvImJ MGP_129S1SvImJ_G0016533
 protein coding gene Chr1:139802055-139832274 (+)
A/J MGP_AJ_G0016516
 protein coding gene Chr1:134513267-134541173 (+)
AKR/J MGP_AKRJ_G0016481
 protein coding gene Chr1:138519385-138546843 (+)
BALB/cJ MGP_BALBcJ_G0016476
 protein coding gene Chr1:134837765-134871771 (+)
C3H/HeJ MGP_C3HHeJ_G0016302
 protein coding gene Chr1:138609279-138637868 (+)
C57BL/6NJ MGP_C57BL6NJ_G0016937
 protein coding gene Chr1:144830074-144859740 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0014648
 protein coding gene Chr1:127618408-127645643 (+)
CAST/EiJ MGP_CASTEiJ_G0015882
 protein coding gene Chr1:137700326-137728913 (+)
CBA/J MGP_CBAJ_G0016275
 protein coding gene Chr1:149845856-149879087 (+)
DBA/2J MGP_DBA2J_G0016381
 protein coding gene Chr1:133509992-133537140 (+)
FVB/NJ MGP_FVBNJ_G0016380
 protein coding gene Chr1:132156225-132183210 (+)
LP/J MGP_LPJ_G0016452
 protein coding gene Chr1:141032372-141062419 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0016405
 protein coding gene Chr1:155493475-155521486 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0016973
 protein coding gene Chr1:138279230-138310412 (+)
PWK/PhJ MGP_PWKPhJ_G0015668
 protein coding gene Chr1:132551132-132579607 (+)
SPRET/EiJ MGP_SPRETEiJ_G0015455
 protein coding gene Chr1:137263804-137292752 (+)
WSB/EiJ MGP_WSBEiJ_G0015945
 protein coding gene Chr1:138325422-138353108 (+)



Homology
more
  • Human Ortholog
    TMEM9, transmembrane protein 9
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TMEM9, transmembrane protein 9
  • Synonyms
    DERM4, TMEM9A
  • Links
    NCBI Gene ID: 252839
    neXtProt AC: NX_Q9P0T7
    UniProt: Q9P0T7

  • Chr Location
    1q32.1; chr1:201134772-201171574 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    4 phenotypes from multigenic genotypes
    13 phenotype references
Mice homozygous for a knock-out allele are viable with no apparent phenotype.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    27
  • GO References
    7
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    786
  • Tissues
    39
  • cDNA Data
    74
  • Literature Summary
    5
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 66241 NCBI Gene Model | MGI Sequence Detail 26812 C57BL/6J ±  kb
transcript NM_001160145 RefSeq | MGI Sequence Detail 1595 Not Specified  
polypeptide Q9CR23 UniProt | EBI | MGI Sequence Detail 183 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    1 Sequence
  • Protein Ontology
    PR:000016439 proton-transporting V-type ATPase complex assembly regulator TMEM9
    (term hierarchy)
  • InterPro Domains
    IPR008853 TMEM9/TMEM9B
  • GlyGen
    Q9CR23 3 sites, 3 N-linked glycans (2 sites)
Molecular
Reagents
less
  • All nucleic 75
    cDNA 74
    Primer pair 1

    Microarray probesets 3
Other
Accession IDs
less
MGI:2138601
References
more
  • Summaries
    All 44
    Developmental Gene Expression 5
    Gene Ontology 7
    Phenotypes 13
  • Earliest
    J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory