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Pdcd5 Gene Detail
Summary
  • Symbol
    Pdcd5
  • Name
    programmed cell death 5
  • Synonyms
    2200003D22Rik, Tfar19
  • Feature Type
    protein coding gene
  • IDs
    MGI:1913538
    NCBI Gene: 56330
  • Alliance
    gene page
  • Transcription Start Sites
    7 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:35341410-35346907 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 7, 21.37 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    266 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1913538
 protein coding gene Chr7:35341407-35346946 (-)
129S1/SvImJ MGP_129S1SvImJ_G0032094
 protein coding gene Chr7:35038117-35045419 (-)
A/J MGP_AJ_G0032074
 protein coding gene Chr7:34110690-34116506 (-)
AKR/J MGP_AKRJ_G0032007
 protein coding gene Chr7:34953884-34961908 (-)
BALB/cJ MGP_BALBcJ_G0032081
 protein coding gene Chr7:34398997-34408307 (-)
C3H/HeJ MGP_C3HHeJ_G0031798
 protein coding gene Chr7:35824491-35830137 (-)
C57BL/6NJ MGP_C57BL6NJ_G0032558
 protein coding gene Chr7:36810023-36817682 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0029591
 protein coding gene Chr7:34863082-34868614 (-)
CAST/EiJ MGP_CASTEiJ_G0031133
 protein coding gene Chr7:27002418-27008933 (-)
CBA/J MGP_CBAJ_G0031766
 protein coding gene Chr7:37924454-37930133 (-)
DBA/2J MGP_DBA2J_G0031918
 protein coding gene Chr7:33955343-33960860 (-)
FVB/NJ MGP_FVBNJ_G0031871
 protein coding gene Chr7:33885660-33891315 (-)
LP/J MGP_LPJ_G0031995
 protein coding gene Chr7:35383017-35390656 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0031911
 protein coding gene Chr7:36925603-36931136 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0032573
 protein coding gene Chr7:34499515-34505000 (-)
PWK/PhJ MGP_PWKPhJ_G0030855
 protein coding gene Chr7:27299933-27305677 (-)
SPRET/EiJ MGP_SPRETEiJ_G0030690
 protein coding gene Chr7:24061102-24066619 (-)
WSB/EiJ MGP_WSBEiJ_G0031243
 protein coding gene Chr7:35041695-35048329 (-)



Homology
more
  • Human Ortholog
    PDCD5, programmed cell death 5
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    PDCD5, programmed cell death 5
  • Synonyms
    TFAR19
  • Links
    NCBI Gene ID: 9141
    neXtProt AC: NX_O14737
    UniProt: O14737

  • Chr Location
    19q13.11; chr19:32581190-32587453 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    10 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    18
  • GO References
    4
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    33
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 56330 NCBI Gene Model | MGI Sequence Detail 5498 C57BL/6J ±  kb
transcript NM_019746 RefSeq | MGI Sequence Detail 642 C57BL/6  
polypeptide P56812 UniProt | EBI | MGI Sequence Detail 126 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 33
    cDNA 33

    Microarray probesets 4
Other
Accession IDs
less
MGI:2138083
References
more
  • Summaries
    All 43
    Developmental Gene Expression 1
    Gene Ontology 4
    Phenotypes 10
  • Earliest
    J:51997 Liu H, et al., TFAR19, a novel apoptosis-related gene cloned from human leukemia cell line TF-1, could enhance apoptosis of some tumor cells induced by growth factor withdrawal. Biochem Biophys Res Commun. 1999 Jan 8;254(1):203-10
  • Latest
    J:306334 Park SY, et al., Club cell-specific role of programmed cell death 5 in pulmonary fibrosis. Nat Commun. 2021 May 19;12(1):2923
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory