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Lsm5 Gene Detail
Summary
  • Symbol
    Lsm5
  • Name
    LSM5 homolog, U6 small nuclear RNA and mRNA degradation associated
  • Synonyms
    2010208O10Rik, 2310034K10Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1913623
    NCBI Gene: 66373
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr6:56678048-56681684 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 6, 27.72 cM, cytoband C1
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    197 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1913623
 protein coding gene Chr6:56678048-56681695 (-)
129S1/SvImJ MGP_129S1SvImJ_G0030779
 protein coding gene Chr6:56156548-56165054 (-)
A/J MGP_AJ_G0030748
 protein coding gene Chr6:53553635-53557050 (-)
AKR/J MGP_AKRJ_G0030675
 protein coding gene Chr6:55346622-55351590 (-)
BALB/cJ MGP_BALBcJ_G0030760
 protein coding gene Chr6:53939688-53943147 (-)
C3H/HeJ MGP_C3HHeJ_G0030473
 protein coding gene Chr6:55402370-55405999 (-)
C57BL/6NJ MGP_C57BL6NJ_G0031215
 protein coding gene Chr6:57426722-57430177 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0028421
 protein coding gene Chr6:51119956-51123579 (-)
CAST/EiJ MGP_CASTEiJ_G0029876
 protein coding gene Chr6:55245326-55248789 (-)
CBA/J MGP_CBAJ_G0030447
 protein coding gene Chr6:59779294-59791042 (-)
DBA/2J MGP_DBA2J_G0030597
 protein coding gene Chr6:53439155-53442839 (-)
FVB/NJ MGP_FVBNJ_G0030549
 protein coding gene Chr6:53032411-53037762 (-)
LP/J MGP_LPJ_G0030682
 protein coding gene Chr6:56081147-56085343 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0030583
 protein coding gene Chr6:62233711-62237906 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0031245
 protein coding gene Chr6:55324971-55330954 (-)
PWK/PhJ MGP_PWKPhJ_G0029589
 protein coding gene Chr6:53122960-53126894 (-)
SPRET/EiJ MGP_SPRETEiJ_G0029423
 protein coding gene Chr6:54724777-54728442 (-)
WSB/EiJ MGP_WSBEiJ_G0029953
 protein coding gene Chr6:55386473-55392048 (-)



Homology
more
  • Human Ortholog
    LSM5, LSM5 homolog, U6 small nuclear RNA and mRNA degradation associated
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    LSM5, LSM5 homolog, U6 small nuclear RNA and mRNA degradation associated
  • Synonyms
    YER146W
  • Links
    NCBI Gene ID: 23658
    neXtProt AC: NX_Q9Y4Y9
    UniProt: Q9Y4Y9

  • Chr Location
    7p14.3; chr7:32485338-32495283 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    21
  • GO References
    7
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    748
  • Tissues
    7
  • cDNA Data
    25
  • Literature Summary
    3
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 66373 NCBI Gene Model | MGI Sequence Detail 3637 C57BL/6J ±  kb
transcript NM_025520 RefSeq | MGI Sequence Detail 516 Not Specified  
polypeptide P62322 UniProt | EBI | MGI Sequence Detail 91 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 25
    cDNA 25

    Microarray probesets 5
Other
Accession IDs
less
MGI:1919345
References
more
  • Summaries
    All 34
    Developmental Gene Expression 3
    Gene Ontology 7
    Phenotypes 4
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:313619 Bedogni F, et al., Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development. Front Mol Neurosci. 2021;14:686034
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory