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Micos10 Gene Detail
Summary
  • Symbol
    Micos10
  • Name
    mitochondrial contact site and cristae organizing system subunit 10
  • Synonyms
    2310028O11Rik, Minos1
  • Feature Type
    protein coding gene
  • IDs
    MGI:1913628
    NCBI Gene: 433771
  • Alliance
    gene page
  • Transcription Start Sites
    6 TSS
Location &
Maps
more
  • Sequence Map
    Chr4:138829125-138858424 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 4, 70.57 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    721 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1913628
 protein coding gene Chr4:138829125-138858667 (-)
129S1/SvImJ MGP_129S1SvImJ_G0029012
 protein coding gene Chr4:141912705-141944789 (-)
A/J MGP_AJ_G0028971
 protein coding gene Chr4:135813337-135842626 (-)
AKR/J MGP_AKRJ_G0028923
 protein coding gene Chr4:139704729-139736509 (-)
BALB/cJ MGP_BALBcJ_G0028995
 protein coding gene Chr4:136493304-136523840 (-)
C3H/HeJ MGP_C3HHeJ_G0028709
 protein coding gene Chr4:140084028-140116573 (-)
C57BL/6NJ MGP_C57BL6NJ_G0029436
 protein coding gene Chr4:146936013-146965296 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0026707
 protein coding gene Chr4:128785019-128815021 (-)
CAST/EiJ MGP_CASTEiJ_G0028141
 protein coding gene Chr4:138269530-138296186 (-)
CBA/J MGP_CBAJ_G0028673
 protein coding gene Chr4:151179783-151226310 (-)
DBA/2J MGP_DBA2J_G0028823
 protein coding gene Chr4:136200468-136243800 (-)
FVB/NJ MGP_FVBNJ_G0028790
 protein coding gene Chr4:135233869-135263585 (-)
LP/J MGP_LPJ_G0028922
 protein coding gene Chr4:141992193-142021497 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0028816
 protein coding gene Chr4:155081468-155112320 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0029474
 protein coding gene Chr4:140231931-140261232 (-)
PWK/PhJ MGP_PWKPhJ_G0027862
 protein coding gene Chr4:133060496-133091333 (-)
SPRET/EiJ MGP_SPRETEiJ_G0027687
 protein coding gene Chr4:135995991-136025353 (-)
WSB/EiJ MGP_WSBEiJ_G0028219
 protein coding gene Chr4:140485541-140516150 (-)



Homology
more
  • Human Ortholog
    MICOS10, mitochondrial contact site and cristae organizing system subunit 10
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    MICOS10, mitochondrial contact site and cristae organizing system subunit 10
  • Synonyms
    C1orf151, Mic10, MINOS1, MIO10
  • Links
    NCBI Gene ID: 440574
    neXtProt AC: NX_Q5TGZ0
    UniProt: Q5TGZ0

  • Chr Location
    1p36.13; chr1:19484403-19629821 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    11 phenotype references
  • All Mutations and Alleles
    16
  • Chemically induced (other)
    2
  • Endonuclease-mediated
    1
  • Gene trapped
    10
  • Targeted
    3
  • Genomic Mutations
    3 involving Micos10
  • Incidental Mutations
    APF
  • Find Mice (IMSR)
    10 strains or lines available
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    6
  • GO References
    5
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    128
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000050608 Ensembl Gene Model | MGI Sequence Detail 29300 C57BL/6J ±  kb
transcript ENSMUST00000143971 Ensembl | MGI Sequence Detail 2549 Not Applicable  
polypeptide ENSMUSP00000117583 Ensembl | MGI Sequence Detail 76 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    1 Sequence
  • InterPro Domains
    IPR007512 MICOS complex subunit Mic10
  • GlyGen
    Q7TNS2 1 site, 1 O-linked glycan (1 site)
Molecular
Reagents
less
  • All nucleic 128
    cDNA 128

    Microarray probesets 5
Other
Accession IDs
less
MGI:6276299
References
more
  • Summaries
    All 35
    Gene Ontology 5
    Phenotypes 11
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory