About   Help   FAQ
Cox14 Gene Detail
Summary
  • Symbol
    Cox14
  • Name
    cytochrome c oxidase assembly protein 14
  • Synonyms
    2310016M24Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1913629
    NCBI Gene: 66379
  • Alliance
    gene page
  • Transcription Start Sites
    8 TSS
Location &
Maps
more
  • Sequence Map
    Chr15:99623499-99626017 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 15, 56.13 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    138 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1913629
 protein coding gene Chr15:99623499-99627413 (+)
129S1/SvImJ MGP_129S1SvImJ_G0022342
 protein coding gene Chr15:101602869-101605172 (+)
A/J MGP_AJ_G0022300
 protein coding gene Chr15:97541500-97543802 (+)
AKR/J MGP_AKRJ_G0022276
 protein coding gene Chr15:100546524-100550618 (+)
BALB/cJ MGP_BALBcJ_G0022306
 protein coding gene Chr15:97726693-97729013 (+)
C3H/HeJ MGP_C3HHeJ_G0022074
 protein coding gene Chr15:100613589-100616868 (+)
C57BL/6NJ MGP_C57BL6NJ_G0022751
 protein coding gene Chr15:105384635-105388315 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0020277
 protein coding gene Chr15:93434548-93436638 (+)
CAST/EiJ MGP_CASTEiJ_G0021598
 protein coding gene Chr15:101482475-101484775 (+)
CBA/J MGP_CBAJ_G0022043
 protein coding gene Chr15:108979007-108986352 (+)
DBA/2J MGP_DBA2J_G0022170
 protein coding gene Chr15:96980105-96985422 (+)
FVB/NJ MGP_FVBNJ_G0022150
 protein coding gene Chr15:95975029-95978109 (+)
LP/J MGP_LPJ_G0022241
 protein coding gene Chr15:101747244-101749557 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0022170
 protein coding gene Chr15:112859770-112862907 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0022766
 protein coding gene Chr15:100662143-100666102 (+)
PWK/PhJ MGP_PWKPhJ_G0021337
 protein coding gene Chr15:97123012-97125469 (+)
SPRET/EiJ MGP_SPRETEiJ_G0021172
 protein coding gene Chr15:100505088-100507466 (+)
WSB/EiJ MGP_WSBEiJ_G0021649
 protein coding gene Chr15:101177772-101181251 (+)



Homology
more
  • Human Ortholog
    COX14, cytochrome c oxidase assembly factor COX14
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    COX14, cytochrome c oxidase assembly factor COX14
  • Synonyms
    C12orf62, MC4DN10, PCAG1
  • Links
    NCBI Gene ID: 84987
    neXtProt AC: NX_Q96I36
    UniProt: Q96I36

  • Chr Location
    12q13.12; chr12:50112082-50120457 (+)  GRCh38
Human Diseases
more
  • Diseases
    1 with human COX14 associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    25 phenotype references
  • All Mutations and Alleles
    12
  • Chemically induced (other)
    1
  • Gene trapped
    8
  • Radiation induced
    2
  • Targeted
    1
  • Genomic Mutations
    3 involving Cox14
  • Find Mice (IMSR)
    3 strains or lines available
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    8
  • GO References
    4
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    62
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 66379 NCBI Gene Model | MGI Sequence Detail 2519 C57BL/6J ±  kb
transcript NM_183256 RefSeq | MGI Sequence Detail 741 C57BL/6  
polypeptide Q8BH51 UniProt | EBI | MGI Sequence Detail 57 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 62
    cDNA 62

    Microarray probesets 3
Other
Accession IDs
less
MGI:2145930
References
more
  • Summaries
    All 51
    Diseases 1
    Gene Ontology 4
    Phenotypes 25
  • Earliest
    J:7688 Lane PW, et al., Association of megacolon with a new dominant spotting gene (Dom) in the mouse. J Hered. 1984 Nov-Dec;75(6):435-9
  • Latest
    J:354134 Aich A, et al., Defective mitochondrial COX1 translation due to loss of COX14 function triggers ROS-induced inflammation in mouse liver. Nat Commun. 2024 Aug 12;15(1):6914
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory