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Mat2b Gene Detail
Summary
  • Symbol
    Mat2b
  • Name
    methionine adenosyltransferase 2 non-catalytic beta subunit methionine
  • Synonyms
    1110064C04Rik, 2410018D16Rik, MATIIbeta
  • Feature Type
    protein coding gene
  • IDs
    MGI:1913667
    NCBI Gene: 108645
  • Alliance
    gene page
  • Transcription Start Sites
    10 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:40570141-40586030 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 11, 24.40 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    519 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1913667
 protein coding gene Chr11:40570141-40586030 (-)
129S1/SvImJ MGP_129S1SvImJ_G0018160
 protein coding gene Chr11:39338889-39354774 (-)
A/J MGP_AJ_G0018133
 protein coding gene Chr11:37847040-37862886 (-)
AKR/J MGP_AKRJ_G0018097
 protein coding gene Chr11:38961394-38977278 (-)
BALB/cJ MGP_BALBcJ_G0018102
 protein coding gene Chr11:38045269-38061194 (-)
C3H/HeJ MGP_C3HHeJ_G0017915
 protein coding gene Chr11:38989293-39006037 (-)
C57BL/6NJ MGP_C57BL6NJ_G0018556
 protein coding gene Chr11:40525515-40544599 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0016211
 protein coding gene Chr11:36077184-36093143 (-)
CAST/EiJ MGP_CASTEiJ_G0017479
 protein coding gene Chr11:39014109-39038776 (-)
CBA/J MGP_CBAJ_G0017888
 protein coding gene Chr11:42434855-42450790 (-)
DBA/2J MGP_DBA2J_G0017998
 protein coding gene Chr11:37603191-37619422 (-)
FVB/NJ MGP_FVBNJ_G0017992
 protein coding gene Chr11:37354637-37370636 (-)
LP/J MGP_LPJ_G0018070
 protein coding gene Chr11:39580568-39596454 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0018016
 protein coding gene Chr11:43731373-43747001 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0018595
 protein coding gene Chr11:39030613-39046502 (-)
PWK/PhJ MGP_PWKPhJ_G0017260
 protein coding gene Chr11:37678586-37694457 (-)
SPRET/EiJ MGP_SPRETEiJ_G0017052
 protein coding gene Chr11:38859581-38876733 (-)
WSB/EiJ MGP_WSBEiJ_G0017528
 protein coding gene Chr11:38749293-38767504 (-)



Homology
more
  • Human Ortholog
    MAT2B, methionine adenosyltransferase 2 non-catalytic beta subunit
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    MAT2B, methionine adenosyltransferase 2 non-catalytic beta subunit
  • Synonyms
    MAT-II, MATIIbeta, Nbla02999, SDR23E1, TGR
  • Links
    NCBI Gene ID: 27430
    neXtProt AC: NX_Q9NZL9
    UniProt: Q9NZL9

  • Chr Location
    5q34; chr5:163503064-163519558 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    13 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    16
  • GO References
    7
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    901
  • Tissues
    126
  • cDNA Data
    183
  • Literature Summary
    7
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 108645 NCBI Gene Model | MGI Sequence Detail 15890 C57BL/6J ±  kb
transcript NM_001199274 RefSeq | MGI Sequence Detail 2066 Not Specified  
polypeptide Q99LB6 UniProt | EBI | MGI Sequence Detail 334 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    2 Sequences
  • Protein Ontology
    PR:000010203 methionine adenosyltransferase 2 subunit beta
    (term hierarchy)
  • InterPro Domains
    IPR005913 dTDP-4-dehydrorhamnose reductase family
    IPR036291 NAD(P)-binding domain superfamily
    IPR029903 RmlD-like substrate binding domain
  • GlyGen
    Q99LB6 1 site, 1 O-linked glycan (1 site)
Molecular
Reagents
less
  • All nucleic 191
    cDNA 184
    Primer pair 7

    Microarray probesets 4
Other
Accession IDs
less
MGI:1916131, MGI:2144077, MGI:2144417
References
more
  • Summaries
    All 50
    Developmental Gene Expression 7
    Gene Ontology 7
    Phenotypes 13
  • Earliest
    J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
  • Latest
    J:312368 Imbard A, et al., Liver and brain differential expression of one-carbon metabolism genes during ontogenesis. Sci Rep. 2021 Oct 26;11(1):21132
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory