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Pomp Gene Detail
Summary
  • Symbol
    Pomp
  • Name
    proteasome maturation protein
  • Synonyms
    2510048O06Rik, Ump1
  • Feature Type
    protein coding gene
  • IDs
    MGI:1913787
    NCBI Gene: 66537
  • Alliance
    gene page
  • Transcription Start Sites
    8 TSS
Location &
Maps
more
  • Sequence Map
    Chr5:147797438-147812594 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 5, 87.52 cM, cytoband G3
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    703 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1913787
 protein coding gene Chr5:147797271-147813266 (+)
129S1/SvImJ MGP_129S1SvImJ_G0030392
 protein coding gene Chr5:153562691-153578468 (+)
A/J MGP_AJ_G0030365
 protein coding gene Chr5:147042022-147057273 (+)
AKR/J MGP_AKRJ_G0030292
 protein coding gene Chr5:151560068-151575040 (+)
BALB/cJ MGP_BALBcJ_G0030374
 protein coding gene Chr5:148261594-148276559 (+)
C3H/HeJ MGP_C3HHeJ_G0030088
 protein coding gene Chr5:152527432-152542409 (+)
C57BL/6NJ MGP_C57BL6NJ_G0030829
 protein coding gene Chr5:159190135-159205139 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0028042
 protein coding gene Chr5:141445708-141460703 (+)
CAST/EiJ MGP_CASTEiJ_G0029490
 protein coding gene Chr5:152104560-152123062 (+)
CBA/J MGP_CBAJ_G0030066
 protein coding gene Chr5:165847068-165862039 (+)
DBA/2J MGP_DBA2J_G0030210
 protein coding gene Chr5:146714656-146729618 (+)
FVB/NJ MGP_FVBNJ_G0030164
 protein coding gene Chr5:145918182-145935558 (+)
LP/J MGP_LPJ_G0030297
 protein coding gene Chr5:154248708-154263745 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0030200
 protein coding gene Chr5:168071478-168086425 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0030859
 protein coding gene Chr5:151477051-151492036 (+)
PWK/PhJ MGP_PWKPhJ_G0029204
 protein coding gene Chr5:145829505-145846377 (+)
SPRET/EiJ MGP_SPRETEiJ_G0029040
 protein coding gene Chr5:148822293-148837219 (+)
WSB/EiJ MGP_WSBEiJ_G0029567
 protein coding gene Chr5:152284349-152299396 (+)



Homology
more
  • Human Ortholog
    POMP, proteasome maturation protein
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    POMP, proteasome maturation protein
  • Synonyms
    C13orf12, HSPC014, PNAS-110, PRAAS2, UMP1
  • Links
    NCBI Gene ID: 51371
    neXtProt AC: NX_Q9Y244
    UniProt: Q9Y244

  • Chr Location
    13q12.3; chr13:28659065-28678959 (+)  GRCh38
Human Diseases
more
  • Diseases
    1 with human POMP associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    13
  • GO References
    6
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    714
  • Tissues
    4
  • cDNA Data
    165
  • Literature Summary
    2
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 66537 NCBI Gene Model | MGI Sequence Detail 15157 C57BL/6J ±  kb
transcript NM_025624 RefSeq | MGI Sequence Detail 740 C57BL/6  
polypeptide Q9CQT5 UniProt | EBI | MGI Sequence Detail 141 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 165
    cDNA 165

    Microarray probesets 3
References
more
  • Summaries
    All 34
    Developmental Gene Expression 2
    Gene Ontology 6
    Phenotypes 6
  • Earliest
    J:63694 Griffin TA, et al., Identification of proteassemblin, a mammalian homologue of the yeast protein, Ump1p, that is required for normal proteasome assembly. Mol Cell Biol Res Commun. 2000 Apr;3(4):212-7
  • Latest
    J:235783 Chu VT, et al., Efficient CRISPR-mediated mutagenesis in primary immune cells using CrispRGold and a C57BL/6 Cas9 transgenic mouse line. Proc Natl Acad Sci U S A. 2016 Nov 1;113(44):12514-12519
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory