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Fam107b Gene Detail
Summary
  • Symbol
    Fam107b
  • Name
    family with sequence similarity 107, member B
  • Synonyms
    3110001A13Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1913790
    NCBI Gene: 66540
  • Alliance
  • Transcription Start Sites
    23 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:3705049-3783179 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 2, 2.05 cM, cytoband A1
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1945 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1913790
protein coding gene Chr2:3571525-3783179 (+)
129S1/SvImJ MGP_129S1SvImJ_G0025312
protein coding gene Chr2:617502-803413 (+)
A/J MGP_AJ_G0025289
protein coding gene Chr2:564069-738684 (+)
AKR/J MGP_AKRJ_G0025257
protein coding gene Chr2:579573-754597 (+)
BALB/cJ MGP_BALBcJ_G0025285
protein coding gene Chr2:549905-725460 (+)
C3H/HeJ MGP_C3HHeJ_G0025045
protein coding gene Chr2:593010-768899 (+)
C57BL/6NJ MGP_C57BL6NJ_G0025727
protein coding gene Chr2:603837-786462 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0023141
protein coding gene Chr2:492752-659342 (+)
CAST/EiJ MGP_CASTEiJ_G0024508
protein coding gene Chr2:592000-770337 (+)
CBA/J MGP_CBAJ_G0025024
protein coding gene Chr2:644182-830933 (+)
DBA/2J MGP_DBA2J_G0025156
protein coding gene Chr2:646450-714765 (+)
FVB/NJ MGP_FVBNJ_G0025118
protein coding gene Chr2:558064-731210 (+)
LP/J MGP_LPJ_G0025242
protein coding gene Chr2:603105-792076 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0025150
protein coding gene Chr2:606186-779947 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0025785
protein coding gene Chr2:587029-759358 (+)
PWK/PhJ MGP_PWKPhJ_G0024258
protein coding gene Chr2:547414-718714 (+)
SPRET/EiJ MGP_SPRETEiJ_G0024059
protein coding gene Chr2:586550-768267 (+)
WSB/EiJ MGP_WSBEiJ_G0024578
protein coding gene Chr2:591388-780537 (+)



Homology
more
  • Human Ortholog
    FAM107B, family with sequence similarity 107 member B
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    FAM107B, family with sequence similarity 107 member B
  • Synonyms
    C10orf45, HITS
  • Links
    NCBI Gene ID: 83641
    neXtProt AC: NX_Q9H098
    UniProt: Q9H098

  • Chr Location
    10p13; chr10:14518557-14774897 (-)  GRCh38

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotypes from 1 allele in 2 genetic backgrounds
    8 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a knock-out allele exhibit impaired hearing.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

Cellular Component

No experimental evidence to support Cellular Component annotation, following literature review. See J:73796.
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 66540 NCBI Gene Model | MGI Sequence Detail 78131 C57BL/6J ±  kb
    transcript NM_001418253 RefSeq | MGI Sequence Detail 3273 C57BL/6  
    polypeptide Q3TGF2 UniProt | EBI | MGI Sequence Detail 131 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 160
      cDNA 160

      Microarray probesets 6
    Other
    Accession IDs
    less
    MGI:2138800, MGI:2138810, MGI:2138843
    References
    more
    • Summaries
      All 36
      Developmental Gene Expression 5
      Gene Ontology 1
      Phenotypes 8
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    last database update
    12/10/2024
    MGI 6.24
    The Jackson Laboratory