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Ube2v1 Gene Detail
Summary
  • Symbol
    Ube2v1
  • Name
    ubiquitin-conjugating enzyme E2 variant 1
  • Synonyms
    0610011J09Rik, CROC1, D7Bwg1382e
  • Feature Type
    protein coding gene
  • IDs
    MGI:1913839
    NCBI Gene: 66589
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:167449559-167473933 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 2, 87.44 cM, cytoband H3
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    597 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1913839
protein coding gene Chr2:167449558-167474015 (-)
129S1/SvImJ MGP_129S1SvImJ_G0026916
protein coding gene Chr2:173360627-173388131 (-)
A/J MGP_AJ_G0026883
protein coding gene Chr2:166216676-166241464 (-)
AKR/J MGP_AKRJ_G0026854
protein coding gene Chr2:171180064-171203062 (-)
BALB/cJ MGP_BALBcJ_G0026892
protein coding gene Chr2:166575065-166601580 (-)
C3H/HeJ MGP_C3HHeJ_G0026634
protein coding gene Chr2:171553416-171576758 (-)
C57BL/6NJ MGP_C57BL6NJ_G0027339
protein coding gene Chr2:178417816-178447998 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0024710
protein coding gene Chr2:159530538-159554048 (-)
CAST/EiJ MGP_CASTEiJ_G0026092
protein coding gene Chr2:172015890-172040381 (-)
CBA/J MGP_CBAJ_G0026611
protein coding gene Chr2:184979045-185006003 (-)
DBA/2J MGP_DBA2J_G0026749
protein coding gene Chr2:165330806-165353110 (-)
FVB/NJ MGP_FVBNJ_G0026715
protein coding gene Chr2:163867021-163890034 (-)
LP/J MGP_LPJ_G0026850
protein coding gene Chr2:173377218-173406468 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0026734
protein coding gene Chr2:188338061-188365533 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0027396
protein coding gene Chr2:171103995-171134261 (-)
PWK/PhJ MGP_PWKPhJ_G0025829
protein coding gene Chr2:165000554-165027643 (-)
SPRET/EiJ MGP_SPRETEiJ_G0025630
protein coding gene Chr2:170055470-170081535 (-)
WSB/EiJ MGP_WSBEiJ_G0026165
protein coding gene Chr2:172016860-172042813 (-)



Homology
more
  • Human Ortholog
    PEDS1-UBE2V1, PEDS1-UBE2V1 readthrough
  • Vertebrate Orthologs
    5
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    PEDS1-UBE2V1, PEDS1-UBE2V1 readthrough
  • Synonyms
    CROC-1B, CROC1B, KUA-UEV, TMEM189-UBE2V1
  • Links
    NCBI Gene ID: 387522
    neXtProt AC: NX_A5PLL7, NX_Q13404

  • Chr Location
    20q13.13; chr20:50081124-50153723 (-)  GRCh38

  • Human Ortholog
    UBE2V1, ubiquitin conjugating enzyme E2 V1
  • Synonyms
    CIR1, CROC-1, CROC1, UBE2V, UEV-1, UEV1, UEV1A
  • Links
    NCBI Gene ID: 7335
    neXtProt AC: NX_Q13404
    UniProt: Q13404

  • Chr Location
    20q13.13; chr20:50081124-50115959 (-)  GRCh38

Mutations,
Alleles, and
Phenotypes
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Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • cDNA Data
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 66589 NCBI Gene Model | MGI Sequence Detail 24375 C57BL/6J ±  kb
transcript NM_001311131 RefSeq | MGI Sequence Detail 2069 ZRU/MplStud  
polypeptide Q9CZY3 UniProt | EBI | MGI Sequence Detail 147 Not Applicable  
For the selected sequence
Protein
Information
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  • UniProt
    4 Sequences
  • Protein Ontology
    PR:000003291 ubiquitin-conjugating enzyme E2 variant 1
  • InterPro Domains
    IPR000608 Ubiquitin-conjugating enzyme E2
    IPR016135 Ubiquitin-conjugating enzyme/RWD-like
  • GlyGen
    Q9CZY3 1 site, 1 O-linked glycan (1 site)
Molecular
Reagents
less
  • All nucleic 14
    cDNA 13
    Primer pair 1

    Microarray probesets 6
Other
Accession IDs
less
MGD-MRK-34145, MGI:106451, MGI:2138870
References
more
  • Summaries
    All 35
    Gene Ontology 10
  • Earliest
    J:214866 JACKSON BR, et al., Recurrent carcinoma of the rectum, surgical treatment. Calif Med. 1959 Sep;91:149-50
  • Latest
    J:205449 Dauphinee SM, et al., SASH1 is a scaffold molecule in endothelial TLR4 signaling. J Immunol. 2013 Jul 15;191(2):892-901

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory