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Lrrc57 Gene Detail
Summary
  • Symbol
    Lrrc57
  • Name
    leucine rich repeat containing 57
  • Synonyms
    2810002D13Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1913856
    NCBI Gene: 66606
  • Alliance
    gene page
  • Transcription Start Sites
    6 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:120434719-120439989 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 2, 60.37 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    181 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1913856
 protein coding gene Chr2:120434719-120440001 (-)
129S1/SvImJ MGP_129S1SvImJ_G0026370
 protein coding gene Chr2:123471808-123477099 (-)
A/J MGP_AJ_G0026331
 protein coding gene Chr2:118421860-118427141 (-)
AKR/J MGP_AKRJ_G0026310
 protein coding gene Chr2:121725963-121731254 (-)
BALB/cJ MGP_BALBcJ_G0026344
 protein coding gene Chr2:118658773-118664054 (-)
C3H/HeJ MGP_C3HHeJ_G0026090
 protein coding gene Chr2:122217100-122222391 (-)
C57BL/6NJ MGP_C57BL6NJ_G0026791
 protein coding gene Chr2:127500025-127505307 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0024171
 protein coding gene Chr2:113436446-113441721 (-)
CAST/EiJ MGP_CASTEiJ_G0025552
 protein coding gene Chr2:122519393-122524685 (-)
CBA/J MGP_CBAJ_G0026066
 protein coding gene Chr2:131962561-131967852 (-)
DBA/2J MGP_DBA2J_G0026205
 protein coding gene Chr2:117813691-117818972 (-)
FVB/NJ MGP_FVBNJ_G0026167
 protein coding gene Chr2:116646480-116651771 (-)
LP/J MGP_LPJ_G0026306
 protein coding gene Chr2:123737640-123742931 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0026186
 protein coding gene Chr2:136271083-136276374 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0026846
 protein coding gene Chr2:121856678-121861969 (-)
PWK/PhJ MGP_PWKPhJ_G0025288
 protein coding gene Chr2:117415887-117421246 (-)
SPRET/EiJ MGP_SPRETEiJ_G0025087
 protein coding gene Chr2:121060805-121066098 (-)
WSB/EiJ MGP_WSBEiJ_G0025621
 protein coding gene Chr2:122686301-122691593 (-)



Homology
more
  • Human Ortholog
    LRRC57, leucine rich repeat containing 57
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    LRRC57, leucine rich repeat containing 57
  • Links
    NCBI Gene ID: 255252
    neXtProt AC: NX_Q8N9N7
    UniProt: Q8N9N7

  • Chr Location
    15q15.2; chr15:42528327-42548802 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotype references
  • All Mutations and Alleles
    5
  • Chemically induced (other)
    1
  • Gene trapped
    1
  • Radiation induced
    1
  • Targeted
    2
  • Genomic Mutations
    2 involving Lrrc57
  • Incidental Mutations
    APF
  • Find Mice (IMSR)
    7 strains or lines available
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    1
  • GO References
    1
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    48
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 66606 NCBI Gene Model | MGI Sequence Detail 5271 C57BL/6J ±  kb
transcript NM_001159612 RefSeq | MGI Sequence Detail 1982 C57BL/6  
polypeptide Q9D1G5 UniProt | EBI | MGI Sequence Detail 239 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 48
    cDNA 48

    Microarray probesets 4
Other
Accession IDs
less
MGI:2138742
References
more
  • Summaries
    All 29
    Gene Ontology 1
    Phenotypes 6
  • Earliest
    J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
  • Latest
    J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory