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Pnisr Gene Detail
Summary
  • Symbol
    Pnisr
  • Name
    PNN interacting serine/arginine-rich
  • Synonyms
    5730406M06Rik, Sfrs18
  • Feature Type
    protein coding gene
  • IDs
    MGI:1913875
    NCBI Gene: 66625
  • Alliance
    gene page
  • Transcription Start Sites
    11 TSS
Location &
Maps
more
  • Sequence Map
    Chr4:21847583-21876475 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 4, 9.06 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    718 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1913875
 protein coding gene Chr4:21846621-21876475 (+)
129S1/SvImJ MGP_129S1SvImJ_G0028093
 protein coding gene Chr4:18871584-18899276 (+)
A/J MGP_AJ_G0028051
 protein coding gene Chr4:18310815-18339491 (+)
AKR/J MGP_AKRJ_G0028016
 protein coding gene Chr4:18731118-18758933 (+)
BALB/cJ MGP_BALBcJ_G0028062
 protein coding gene Chr4:18365247-18397879 (+)
C3H/HeJ MGP_C3HHeJ_G0027792
 protein coding gene Chr4:18899316-18927573 (+)
C57BL/6NJ MGP_C57BL6NJ_G0028505
 protein coding gene Chr4:19635645-19665625 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0025847
 protein coding gene Chr4:16975148-17004033 (+)
CAST/EiJ MGP_CASTEiJ_G0027247
 protein coding gene Chr4:18669205-18699354 (+)
CBA/J MGP_CBAJ_G0027765
 protein coding gene Chr4:20200640-20231804 (+)
DBA/2J MGP_DBA2J_G0027908
 protein coding gene Chr4:18181163-18208935 (+)
FVB/NJ MGP_FVBNJ_G0027874
 protein coding gene Chr4:17894060-17921816 (+)
LP/J MGP_LPJ_G0028017
 protein coding gene Chr4:18946424-18975675 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0027907
 protein coding gene Chr4:21429788-21458002 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0028564
 protein coding gene Chr4:18690429-18718300 (+)
PWK/PhJ MGP_PWKPhJ_G0026967
 protein coding gene Chr4:18015045-18043398 (+)
SPRET/EiJ MGP_SPRETEiJ_G0026796
 protein coding gene Chr4:18498498-18527521 (+)
WSB/EiJ MGP_WSBEiJ_G0027324
 protein coding gene Chr4:18679951-18709560 (+)



Homology
more
  • Human Ortholog
    PNISR, PNN interacting serine and arginine rich protein
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    PNISR, PNN interacting serine and arginine rich protein
  • Synonyms
    bA98I9.2, C6orf111, HSPC306, SFRS18, SRrp130
  • Links
    NCBI Gene ID: 25957
    neXtProt AC: NX_Q8TF01
    UniProt: Q8TF01

  • Chr Location
    6q16.2; chr6:99397629-99425331 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotypes from 1 allele in 1 genetic background
    10 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    7
  • GO References
    3
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    834
  • Tissues
    26
  • cDNA Data
    195
  • Literature Summary
    3
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000028248 Ensembl Gene Model | MGI Sequence Detail 28893 C57BL/6J ±  kb
transcript ENSMUST00000029911 Ensembl | MGI Sequence Detail 4545 Not Applicable  
polypeptide ENSMUSP00000029911 Ensembl | MGI Sequence Detail 814 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    7 Sequences
  • Protein Ontology
    PR:000014756 arginine/serine-rich protein PNISR
    (term hierarchy)
  • InterPro Domains
    IPR031937 PNN-interacting serine/arginine-rich protein
  • GlyGen
    A2AJT4 3 sites, 2 N-linked glycans (3 sites)
Molecular
Reagents
less
  • All nucleic 200
    cDNA 200

    Microarray probesets 12
Other
Accession IDs
less
MGI:2140171
References
more
  • Summaries
    All 37
    Developmental Gene Expression 3
    Gene Ontology 3
    Phenotypes 10
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:279139 Cibi DM, et al., Neural crest-specific deletion of Rbfox2 in mice leads to craniofacial abnormalities including cleft palate. Elife. 2019 Jun 26;8:e45418
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory