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Cdip1 Gene Detail
Summary
  • Symbol
    Cdip1
  • Name
    cell death inducing Trp53 target 1
  • Synonyms
    2700048O17Rik, 5730403B10Rik, CDIP
  • Feature Type
    protein coding gene
  • IDs
    MGI:1913876
    NCBI Gene: 66626
  • Alliance
    gene page
  • Transcription Start Sites
    9 TSS
Location &
Maps
more
  • Sequence Map
    Chr16:4583325-4608156 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 16, 2.47 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    439 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1913876
 protein coding gene Chr16:4568212-4608156 (-)
129S1/SvImJ MGP_129S1SvImJ_G0022472
 protein coding gene Chr16:1272405-1297285 (-)
A/J MGP_AJ_G0022434
 protein coding gene Chr16:1069854-1112706 (-)
AKR/J MGP_AKRJ_G0022411
 protein coding gene Chr16:1263142-1306851 (-)
BALB/cJ MGP_BALBcJ_G0022439
 protein coding gene Chr16:1245151-1270036 (-)
C3H/HeJ MGP_C3HHeJ_G0022206
 protein coding gene Chr16:1286719-1326941 (-)
C57BL/6NJ MGP_C57BL6NJ_G0022888
 protein coding gene Chr16:1359068-1383941 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0020409
 protein coding gene Chr16:1018711-1058695 (-)
CAST/EiJ MGP_CASTEiJ_G0021732
 protein coding gene Chr16:1275485-1323231 (-)
CBA/J MGP_CBAJ_G0022175
 protein coding gene Chr16:1403803-1446349 (-)
DBA/2J MGP_DBA2J_G0022306
 protein coding gene Chr16:1183212-1224795 (-)
FVB/NJ MGP_FVBNJ_G0022281
 protein coding gene Chr16:1172572-1211371 (-)
LP/J MGP_LPJ_G0022374
 protein coding gene Chr16:1253984-1294321 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0022303
 protein coding gene Chr16:1288896-1314924 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0022900
 protein coding gene Chr16:1236569-1277153 (-)
PWK/PhJ MGP_PWKPhJ_G0021472
 protein coding gene Chr16:1251821-1288457 (-)
SPRET/EiJ MGP_SPRETEiJ_G0021303
 protein coding gene Chr16:1329748-1371149 (-)
WSB/EiJ MGP_WSBEiJ_G0021781
 protein coding gene Chr16:1249455-1288114 (-)



Homology
more
  • Human Ortholog
    CDIP1, cell death inducing p53 target 1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CDIP1, cell death inducing p53 target 1
  • Synonyms
    C16orf5, CDIP, I1, LITAFL
  • Links
    NCBI Gene ID: 29965
    neXtProt AC: NX_Q9H305
    UniProt: Q9H305

  • Chr Location
    16p13.3; chr16:4510669-4538828 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotypes from 2 alleles in 2 genetic backgrounds
    9 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Homozygous KO impairs (protects against) ER-stress-induced cell death in the liver.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    14
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    716
  • Tissues
    3
  • cDNA Data
    17
  • Literature Summary
    2
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 66626 NCBI Gene Model | MGI Sequence Detail 24832 C57BL/6J ±  kb
transcript NM_001358079 RefSeq | MGI Sequence Detail 3974 ZRU/MplStud  
polypeptide Q9DB75 UniProt | EBI | MGI Sequence Detail 208 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 19
    cDNA 19

    Microarray probesets 7
Other
Accession IDs
less
MGI:1919832, MGI:2146549, MGI:2146673
References
more
  • Summaries
    All 39
    Developmental Gene Expression 2
    Gene Ontology 5
    Phenotypes 9
  • Earliest
    J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory