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Tpgs2 Gene Detail
Summary
  • Symbol
    Tpgs2
  • Name
    tubulin polyglutamylase complex subunit 2
  • Synonyms
    5730437P09Rik, 5730494M16Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1913898
    NCBI Gene: 66648
  • Alliance
    gene page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr18:25260280-25301990 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 18, 13.69 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1311 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1913898
 protein coding gene Chr18:25260280-25302064 (-)
129S1/SvImJ MGP_129S1SvImJ_G0024207
 protein coding gene Chr18:22932587-22977371 (-)
A/J MGP_AJ_G0024172
 protein coding gene Chr18:22274914-22316336 (-)
AKR/J MGP_AKRJ_G0024141
 protein coding gene Chr18:22930745-22993942 (-)
BALB/cJ MGP_BALBcJ_G0024172
 protein coding gene Chr18:22336992-22379723 (-)
C3H/HeJ MGP_C3HHeJ_G0023940
 protein coding gene Chr18:22879599-22927154 (-)
C57BL/6NJ MGP_C57BL6NJ_G0024614
 protein coding gene Chr18:23854503-23899972 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0022056
 protein coding gene Chr18:22104081-22144504 (-)
CAST/EiJ MGP_CASTEiJ_G0023414
 protein coding gene Chr18:22682671-22727640 (-)
CBA/J MGP_CBAJ_G0023908
 protein coding gene Chr18:24506677-24556047 (-)
DBA/2J MGP_DBA2J_G0024040
 protein coding gene Chr18:21924052-21965398 (-)
FVB/NJ MGP_FVBNJ_G0024006
 protein coding gene Chr18:21706115-21747358 (-)
LP/J MGP_LPJ_G0024121
 protein coding gene Chr18:23066246-23112176 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0024034
 protein coding gene Chr18:25513745-25562297 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0024662
 protein coding gene Chr18:22710899-22756771 (-)
PWK/PhJ MGP_PWKPhJ_G0023158
 protein coding gene Chr18:22074622-22117479 (-)
SPRET/EiJ MGP_SPRETEiJ_G0022967
 protein coding gene Chr18:22932013-22975325 (-)
WSB/EiJ MGP_WSBEiJ_G0023478
 protein coding gene Chr18:22594809-22638195 (-)



Homology
more
  • Human Ortholog
    TPGS2, tubulin polyglutamylase complex subunit 2
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TPGS2, tubulin polyglutamylase complex subunit 2
  • Synonyms
    C18orf10, HMFN0601, L17, PGs2
  • Links
    NCBI Gene ID: 25941
    neXtProt AC: NX_Q68CL5
    UniProt: Q68CL5

  • Chr Location
    18q12.2; chr18:36777647-36829216 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    10 phenotypes from 1 allele in 1 genetic background
    8 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    2
  • GO References
    2
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    833
  • Tissues
    46
  • cDNA Data
    12
  • Literature Summary
    2
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 66648 NCBI Gene Model | MGI Sequence Detail 41711 C57BL/6J ±  kb
    transcript NM_001004361 RefSeq | MGI Sequence Detail 4040 C57BL/6  
    polypeptide Q66JT5 UniProt | EBI | MGI Sequence Detail 296 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 13
      cDNA 13

      Microarray probesets 7
    Other
    Accession IDs
    less
    MGI:1917781, MGI:2147259
    References
    more
    • Summaries
      All 34
      Developmental Gene Expression 2
      Gene Ontology 2
      Phenotypes 8
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    11/12/2024
    MGI 6.24     		The Jackson Laboratory