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Tmed7 Gene Detail
Summary
  • Symbol
    Tmed7
  • Name
    transmembrane p24 trafficking protein 7
  • Synonyms
    3930401E15Rik, 5830493P14Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1913926
    NCBI Gene: 66676
  • Alliance
    gene page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr18:46718995-46730602 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 18, 24.65 cM, cytoband C
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    359 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1913926
 protein coding gene Chr18:46693302-46730602 (-)
129S1/SvImJ MGP_129S1SvImJ_G0024409
 protein coding gene Chr18:45371439-45407084 (-)
A/J MGP_AJ_G0024376
 protein coding gene Chr18:43740515-43778743 (-)
AKR/J MGP_AKRJ_G0024345
 protein coding gene Chr18:44935854-44974907 (-)
BALB/cJ MGP_BALBcJ_G0024376
 protein coding gene Chr18:43838473-43877148 (-)
C3H/HeJ MGP_C3HHeJ_G0024143
 protein coding gene Chr18:45027033-45063493 (-)
C57BL/6NJ MGP_C57BL6NJ_G0024820
 protein coding gene Chr18:46969759-47011720 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0022255
 protein coding gene Chr18:43563012-43594671 (-)
CAST/EiJ MGP_CASTEiJ_G0023617
 protein coding gene Chr18:44978229-45013392 (-)
CBA/J MGP_CBAJ_G0024112
 protein coding gene Chr18:48236148-48281369 (-)
DBA/2J MGP_DBA2J_G0024242
 protein coding gene Chr18:43347608-43385083 (-)
FVB/NJ MGP_FVBNJ_G0024208
 protein coding gene Chr18:42912818-42952119 (-)
LP/J MGP_LPJ_G0024326
 protein coding gene Chr18:45440196-45480552 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0024239
 protein coding gene Chr18:49586183-49628524 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0024867
 protein coding gene Chr18:44856569-44895806 (-)
PWK/PhJ MGP_PWKPhJ_G0023361
 protein coding gene Chr18:43492203-43528658 (-)
SPRET/EiJ MGP_SPRETEiJ_G0023166
 protein coding gene Chr18:45004830-45041371 (-)
WSB/EiJ MGP_WSBEiJ_G0023680
 protein coding gene Chr18:44752634-44790544 (-)



Homology
more
  • Human Ortholog
    TMED7, transmembrane p24 trafficking protein 7
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TMED7, transmembrane p24 trafficking protein 7
  • Synonyms
    CGI-109, p24g3, p24gamma3, p27, Tag
  • Links
    NCBI Gene ID: 51014
    neXtProt AC: NX_Q9Y3B3
    UniProt: Q9Y3B3

  • Chr Location
    5q22.3; chr5:115613210-115632992 (-)  GRCh38
  • Human Ortholog
    TMED7-TICAM2, TMED7-TICAM2 readthrough
  • Synonyms
    MyD88-4, TICAM-2, TICAM2, TIRAP3, TIRP, TRAM
  • Links
    NCBI Gene ID: 100302736
    neXtProt AC: NX_Q86XR7, NX_Q9Y3B3

  • Chr Location
    chr5:115578496-115626161 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotype references
  • All Mutations and Alleles
    8
  • Endonuclease-mediated
    2
  • Gene trapped
    3
  • Spontaneous
    1
  • Targeted
    2
  • Genomic Mutations
    1 involving Tmed7
  • Find Mice (IMSR)
    12 strains or lines available
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    10
  • GO References
    2
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    711
  • Tissues
    1
  • cDNA Data
    150
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 66676 NCBI Gene Model | MGI Sequence Detail 11608 C57BL/6J ±  kb
transcript NM_025698 RefSeq | MGI Sequence Detail 3452 C57BL/6  
polypeptide NP_079974 RefSeq | MGI Sequence Detail 224 C57BL/6  
For the selected sequence
Protein
Information
less
  • UniProt
    2 Sequences
  • InterPro Domains
    IPR009038 GOLD domain
    IPR036598 GOLD domain superfamily
    IPR015720 Transmembrane emp24 domain-containing protein
Molecular
Reagents
less
  • All nucleic 152
    cDNA 151
    Primer pair 1

    Microarray probesets 9
Other
Accession IDs
less
MGI:1923362, MGI:2147327, MGI:2147370
References
more
  • Summaries
    All 33
    Developmental Gene Expression 1
    Gene Ontology 2
    Phenotypes 7
  • Earliest
    J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
  • Latest
    J:327181 Lewis MA, et al., Identification and characterisation of spontaneous mutations causing deafness from a targeted knockout programme. BMC Biol. 2022 Mar 17;20(1):67
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory