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Tmem186 Gene Detail
Summary
  • Symbol
    Tmem186
  • Name
    transmembrane protein 186
  • Synonyms
    2810440M13Rik, 4432406C05Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1913940
    NCBI Gene: 66690
  • Alliance
    gene page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr16:8451595-8455575 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 16, 4.24 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    228 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1913940
 protein coding gene Chr16:8451093-8455576 (-)
129S1/SvImJ MGP_129S1SvImJ_G0022495
 protein coding gene Chr16:5299612-5303438 (-)
A/J MGP_AJ_G0022457
 protein coding gene Chr16:4988522-4992349 (-)
AKR/J MGP_AKRJ_G0022433
 protein coding gene Chr16:5265697-5269524 (-)
BALB/cJ MGP_BALBcJ_G0022461
 protein coding gene Chr16:5159500-5163325 (-)
C3H/HeJ MGP_C3HHeJ_G0022228
 protein coding gene Chr16:5302709-5306538 (-)
C57BL/6NJ MGP_C57BL6NJ_G0022910
 protein coding gene Chr16:5448462-5452287 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0020431
 protein coding gene Chr16:5188110-5191946 (-)
CAST/EiJ MGP_CASTEiJ_G0021755
 protein coding gene Chr16:5321771-5325593 (-)
CBA/J MGP_CBAJ_G0022197
 protein coding gene Chr16:5658156-5661985 (-)
DBA/2J MGP_DBA2J_G0022328
 protein coding gene Chr16:5035789-5039610 (-)
FVB/NJ MGP_FVBNJ_G0022304
 protein coding gene Chr16:5016560-5020389 (-)
LP/J MGP_LPJ_G0022396
 protein coding gene Chr16:5275174-5279003 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0022326
 protein coding gene Chr16:5448020-5451849 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0022923
 protein coding gene Chr16:5214561-5218390 (-)
PWK/PhJ MGP_PWKPhJ_G0021495
 protein coding gene Chr16:5206189-5210063 (-)
SPRET/EiJ MGP_SPRETEiJ_G0021325
 protein coding gene Chr16:5269387-5273700 (-)
WSB/EiJ MGP_WSBEiJ_G0021803
 protein coding gene Chr16:5249798-5253620 (-)



Homology
more
  • Human Ortholog
    TMEM186, transmembrane protein 186
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TMEM186, transmembrane protein 186
  • Synonyms
    C16orf51
  • Links
    NCBI Gene ID: 25880
    neXtProt AC: NX_Q96B77
    UniProt: Q96B77

  • Chr Location
    16p13.2; chr16:8780384-8797642 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    6
  • GO References
    5
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    16
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 66690 NCBI Gene Model | MGI Sequence Detail 3981 C57BL/6J ±  kb
transcript NM_025708 RefSeq | MGI Sequence Detail 2888 C57BL/6  
polypeptide Q9CR76 UniProt | EBI | MGI Sequence Detail 216 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 16
    cDNA 16

    Microarray probesets 7
Other
Accession IDs
less
MGI:1914477, MGI:2146474, MGI:2146628
References
more
  • Summaries
    All 33
    Gene Ontology 5
    Phenotypes 7
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:151002 Pagliarini DJ, et al., A mitochondrial protein compendium elucidates complex I disease biology. Cell. 2008 Jul 11;134(1):112-23
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory