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Capza1b Gene Detail
Summary
  • Symbol
    Capza1b
  • Name
    capping actin protein of muscle Z-line subunit alpha 1B
  • Synonyms
    4933400A11Rik
Location &
Maps
more
  • Sequence Map
    ChrX:168559374-168562631 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome X, 79.23 cM, cytoband F5
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    132 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1913997
 protein coding gene ChrX:168559253-168562631 (-)
129S1/SvImJ MGP_129S1SvImJ_G0036278
 protein coding gene ChrX:167984629-167989322 (-)
A/J MGP_AJ_G0036248
 protein coding gene ChrX:167107509-167111296 (-)
AKR/J MGP_AKRJ_G0036177
 protein coding gene ChrX:172458145-172461619 (-)
BALB/cJ MGP_BALBcJ_G0036242
 protein coding gene ChrX:165063062-165066573 (-)
C3H/HeJ MGP_C3HHeJ_G0035950
 protein coding gene ChrX:168323396-168327996 (-)
C57BL/6NJ MGP_C57BL6NJ_G0036766
 protein coding gene ChrX:172855604-172858842 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0033585
 protein coding gene ChrX:157785472-157788788 (-)
CAST/EiJ MGP_CASTEiJ_G0035236
 protein coding gene ChrX:147154068-147158504 (-)
CBA/J MGP_CBAJ_G0035923
 protein coding gene ChrX:177875216-177880013 (-)
DBA/2J MGP_DBA2J_G0036090
 protein coding gene ChrX:165875892-165879161 (-)
FVB/NJ MGP_FVBNJ_G0036021
 protein coding gene ChrX:165018551-165021652 (-)
LP/J MGP_LPJ_G0036174
 protein coding gene ChrX:169081464-169085019 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0036053
 protein coding gene ChrX:186680729-186684538 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0036805
 protein coding gene ChrX:167478097-167482582 (-)
PWK/PhJ MGP_PWKPhJ_G0034936
 protein coding gene ChrX:143844527-143847958 (-)
SPRET/EiJ MGP_SPRETEiJ_G0034754
 protein coding gene ChrX:147764644-147767895 (-)
WSB/EiJ MGP_WSBEiJ_G0035372
 protein coding gene ChrX:165263437-165267768 (-)



Homology
more
  • Human Ortholog
    CAPZA1, capping actin protein of muscle Z-line subunit alpha 1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CAPZA1, capping actin protein of muscle Z-line subunit alpha 1
  • Synonyms
    CAPPA1, CAPZ, CAZ1
  • Links
    NCBI Gene ID: 829
    neXtProt AC: NX_P52907
    UniProt: P52907

  • Chr Location
    1p13.2; chr1:112619805-112671616 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    7
  • GO References
    2
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    5
Sequences &
Gene Models
less
  • All Sequences
    33
  • RefSeq
    1
  • UniProt
    1
Representative SequencesLengthStrain/SpeciesFlank
genomic 66747 NCBI Gene Model | MGI Sequence Detail 3258 C57BL/6J ±  kb
transcript NR_003635 RefSeq | MGI Sequence Detail 1230 C57BL/6  
polypeptide Q9CR52 UniProt | EBI | MGI Sequence Detail 288 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    1 Sequence
  • InterPro Domains
    IPR042489 F-actin capping protein, alpha subunit, domain 1
    IPR002189 F-actin-capping protein subunit alpha
    IPR037282 F-actin-capping protein subunit alpha/beta
    IPR042276 F-actin-capping protein subunit alpha/beta, domain 2
Molecular
Reagents
less
  • All nucleic 5
    cDNA 5

    Microarray probesets 2
Other
Accession IDs
less
MGI:7280772
References
more
  • Summaries
    All 17
    Gene Ontology 2
    Phenotypes 2
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/05/2024
MGI 6.24 		The Jackson Laboratory