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Clec14a Gene Detail
Summary
  • Symbol
    Clec14a
  • Name
    C-type lectin domain family 14, member a
  • Synonyms
    1200003C23Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1914114
    NCBI Gene: 66864
  • Alliance
    genome feature page
  • Transcription Start Sites
    6 TSS
Location &
Maps
more
  • Sequence Map
    Chr12:58311506-58316044 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 12, 25.65 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    167 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1914114
 protein coding gene Chr12:58311506-58316076 (-)
129S1/SvImJ ENSMUSG00200029058
 protein coding gene Chr12:50206149-50210719 (-)
A/J ENSMUSG00195001603
 protein coding gene Chr12:52807565-52812138 (-)
AKR/J ENSMUSG00220015699
 protein coding gene Chr12:50876531-50881101 (-)
BALB/cJ ENSMUSG00180007072
 protein coding gene Chr12:51821840-51826413 (-)
C3H/HeJ ENSMUSG00175015835
 protein coding gene Chr12:54862831-54867404 (-)
C57BL/6NJ ENSMUSG00215007054
 protein coding gene Chr12:51158162-51162732 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0017775
 protein coding gene Chr12:53760508-53765055 (-)
CAST/EiJ ENSTCUG00005012327
 protein coding gene Chr12:51251813-51256386 (-)
CBA/J ENSMUSG00210014135
 protein coding gene Chr12:51337088-51341661 (-)
DBA/2J ENSMUSG00185000906
 protein coding gene Chr12:53282334-53286907 (-)
FVB/NJ ENSMUSG00205005615
 protein coding gene Chr12:51126449-51131022 (-)
JF1/MsJ ENSUMUG00000006031
 protein coding gene Chr12:57351684-57356255 (-)
LP/J ENSMUSG00230015711
 protein coding gene Chr12:60309804-60314374 (-)
NOD/ShiLtJ ENSMUSG00190015385
 protein coding gene Chr12:50330732-50335305 (-)
NZO/HlLtJ ENSMUSG00225029618
 protein coding gene Chr12:62454651-62459221 (-)
PWK/PhJ ENSLUMG00010002415
 protein coding gene Chr12:51405868-51410442 (-)
SPRET/EiJ ENSMSPG00010010966
 protein coding gene Chr12:52897462-52899395 (-)
WSB/EiJ ENSIUOG00005000921
 protein coding gene Chr12:51183056-51187626 (-)



Homology
more
  • Human Ortholog
    CLEC14A, C-type lectin domain containing 14A
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CLEC14A, C-type lectin domain containing 14A
  • Synonyms
    C14orf27, CEG1, EGFR-5
  • Links
    NCBI Gene ID: 161198
    UniProt: Q86T13

  • Chr Location
    14q21.1; chr14:38254000-38256093 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    12 phenotype references
No notable pheontype was detected in a high-throughput screen of homozygous mutant mice.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    23
  • GO References
    8
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    668
  • Tissues
    8
  • cDNA Data
    35
  • Literature Summary
    7
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 66864 NCBI Gene Model | MGI Sequence Detail 4539 C57BL/6J ±  kb
transcript NM_025809 RefSeq | MGI Sequence Detail 4539 C57BL/6  
polypeptide Q8VCP9 UniProt | EBI | MGI Sequence Detail 459 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 37
    Genomic 1
    cDNA 35
    Primer pair 1

    Microarray probesets 4
Other
Accession IDs
less
MGI:2144870
References
more
  • Summaries
    All 48
    Developmental Gene Expression 7
    Gene Ontology 8
    Phenotypes 12
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:375526 Luo PM, et al., Zonal endothelial cell heterogeneity underlies murine renal vascular development. Angiogenesis. 2025 Oct 16;28(4):57
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/01/2026
MGI 6.24 		The Jackson Laboratory