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Crnkl1 Gene Detail
Summary
  • Symbol
    Crnkl1
  • Name
    crooked neck pre-mRNA splicing factor 1
  • Synonyms
    1200013P10Rik, 5730590A01Rik, crn
  • Feature Type
    protein coding gene
  • IDs
    MGI:1914127
    NCBI Gene: 66877
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:145759402-145776620 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 2, 71.28 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    455 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1914127
 protein coding gene Chr2:145759399-145776934 (-)
129S1/SvImJ MGP_129S1SvImJ_G0026596
 protein coding gene Chr2:150085659-150103092 (-)
A/J MGP_AJ_G0026560
 protein coding gene Chr2:144018057-144034106 (-)
AKR/J MGP_AKRJ_G0026534
 protein coding gene Chr2:148192923-148210300 (-)
BALB/cJ MGP_BALBcJ_G0026572
 protein coding gene Chr2:144441900-144459239 (-)
C3H/HeJ MGP_C3HHeJ_G0026315
 protein coding gene Chr2:148674017-148691305 (-)
C57BL/6NJ MGP_C57BL6NJ_G0027017
 protein coding gene Chr2:154522781-154540160 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0024394
 protein coding gene Chr2:138136727-138154109 (-)
CAST/EiJ MGP_CASTEiJ_G0025776
 protein coding gene Chr2:149028965-149046257 (-)
CBA/J MGP_CBAJ_G0026295
 protein coding gene Chr2:160131041-160148370 (-)
DBA/2J MGP_DBA2J_G0026429
 protein coding gene Chr2:143309142-143326581 (-)
FVB/NJ MGP_FVBNJ_G0026393
 protein coding gene Chr2:141853831-141871083 (-)
LP/J MGP_LPJ_G0026533
 protein coding gene Chr2:150277936-150295319 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0026413
 protein coding gene Chr2:164330218-164347514 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0027072
 protein coding gene Chr2:148185726-148203096 (-)
PWK/PhJ MGP_PWKPhJ_G0025511
 protein coding gene Chr2:142981670-142999437 (-)
SPRET/EiJ MGP_SPRETEiJ_G0025312
 protein coding gene Chr2:147173653-147192266 (-)
WSB/EiJ MGP_WSBEiJ_G0025849
 protein coding gene Chr2:149122288-149139580 (-)



Homology
more
  • Human Ortholog
    CRNKL1, crooked neck pre-mRNA splicing factor 1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CRNKL1, crooked neck pre-mRNA splicing factor 1
  • Synonyms
    CLF, Clf1, CRN, HCRN, MSTP021, SYF3
  • Links
    NCBI Gene ID: 51340
    neXtProt AC: NX_Q9BZJ0
    UniProt: Q9BZJ0

  • Chr Location
    20p11.23; chr20:20034368-20056046 (-)  GRCh38
Human Diseases
more
  • Diseases
    1 with human CRNKL1 associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    8 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    21
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    730
  • Tissues
    24
  • cDNA Data
    128
  • Literature Summary
    2
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 66877 NCBI Gene Model | MGI Sequence Detail 17219 C57BL/6J ±  kb
transcript NM_025820 RefSeq | MGI Sequence Detail 3111 C57BL/6  
polypeptide P63154 UniProt | EBI | MGI Sequence Detail 690 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 129
    cDNA 128
    Primer pair 1

    Microarray probesets 5
Other
Accession IDs
less
MGI:1924260, MGI:2139502
References
more
  • Summaries
    All 34
    Developmental Gene Expression 2
    Gene Ontology 5
    Phenotypes 8
  • Earliest
    J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
  • Latest
    J:326541 Cyagen Biosciences Inc., Cyagen Biosciences Website. 2022;
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory