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Lonp2 Gene Detail
Summary
  • Symbol
    Lonp2
  • Name
    lon peptidase 2, peroxisomal
  • Synonyms
    1300002A08Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1914137
    NCBI Gene: 66887
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr8:87350672-87443264 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 8, 42.10 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    2600 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1914137
 protein coding gene Chr8:87350672-87450501 (+)
129S1/SvImJ MGP_129S1SvImJ_G0033908
 protein coding gene Chr8:87593835-87703071 (+)
A/J MGP_AJ_G0033891
 protein coding gene Chr8:84161334-84257609 (+)
AKR/J MGP_AKRJ_G0033817
 protein coding gene Chr8:86648888-86751187 (+)
BALB/cJ MGP_BALBcJ_G0033884
 protein coding gene Chr8:84307166-84402182 (+)
C3H/HeJ MGP_C3HHeJ_G0033595
 protein coding gene Chr8:87257305-87356684 (+)
C57BL/6NJ MGP_C57BL6NJ_G0034405
 protein coding gene Chr8:90958338-91064385 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0031345
 protein coding gene Chr8:78194742-78280030 (+)
CAST/EiJ MGP_CASTEiJ_G0032925
 protein coding gene Chr8:86666824-86757627 (+)
CBA/J MGP_CBAJ_G0033570
 protein coding gene Chr8:94043927-94152780 (+)
DBA/2J MGP_DBA2J_G0033723
 protein coding gene Chr8:83770736-83871284 (+)
FVB/NJ MGP_FVBNJ_G0033671
 protein coding gene Chr8:82719125-82818120 (+)
LP/J MGP_LPJ_G0033815
 protein coding gene Chr8:87723109-87824830 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0033714
 protein coding gene Chr8:96570043-96672631 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0034422
 protein coding gene Chr8:86634057-86743323 (+)
PWK/PhJ MGP_PWKPhJ_G0032629
 protein coding gene Chr8:83014151-83113858 (+)
SPRET/EiJ MGP_SPRETEiJ_G0032464
 protein coding gene Chr8:85393358-85494114 (+)
WSB/EiJ MGP_WSBEiJ_G0033037
 protein coding gene Chr8:87071972-87165695 (+)



Homology
more
  • Human Ortholog
    LONP2, lon peptidase 2, peroxisomal
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    LONP2, lon peptidase 2, peroxisomal
  • Synonyms
    LONP, LONPL, PLON, PSLON
  • Links
    NCBI Gene ID: 83752
    neXtProt AC: NX_Q86WA8
    UniProt: Q86WA8

  • Chr Location
    16q12.1; chr16:48244300-48363122 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    34 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    27
  • GO References
    8
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    715
  • Tissues
    5
  • cDNA Data
    150
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 66887 NCBI Gene Model | MGI Sequence Detail 92593 C57BL/6J ±  kb
transcript NM_025827 RefSeq | MGI Sequence Detail 2936 C57BL/6  
polypeptide Q9DBN5 UniProt | EBI | MGI Sequence Detail 852 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 152
    cDNA 150
    Primer pair 1
    Other 1

    Microarray probesets 5
Other
Accession IDs
less
MGI:2142675
References
more
  • Summaries
    All 63
    Developmental Gene Expression 1
    Gene Ontology 8
    Phenotypes 34
  • Earliest
    J:13049 Gruneberg H, Genetical studies on the skeleton of the mouse. XVIII. Three genes for syndactylism. J Genet. 1956;54(1):113-145
  • Latest
    J:348117 Okuma H, et al., N-terminal domain on dystroglycan enables LARGE1 to extend matriglycan on alpha-dystroglycan and prevents muscular dystrophy. Elife. 2023 Feb 1;12
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory