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1700010I14Rik Gene Detail
Summary
  • Symbol
    1700010I14Rik
  • Name
    RIKEN cDNA 1700010I14 gene
  • Feature Type
    protein coding gene
  • IDs
    MGI:1914181
    NCBI Gene: 66931
  • Alliance
    gene page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr17:9207152-9227151 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 17, 5.53 cM, cytoband A1
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    273 from dbSNP Build 142
  • Strain Annotations
    17
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1914181
 protein coding gene Chr17:9207152-9230781 (+)
129S1/SvImJ MGP_129S1SvImJ_G0023138
 protein coding gene Chr17:6487863-6507595 (+)
A/J MGP_AJ_G0023106
 protein coding gene Chr17:6491782-6511699 (+)
AKR/J MGP_AKRJ_G0023070
 protein coding gene Chr17:6191188-6211151 (+)
BALB/cJ MGP_BALBcJ_G0023106
 protein coding gene Chr17:6273971-6299048 (+)
C3H/HeJ MGP_C3HHeJ_G0022869
 protein coding gene Chr17:6456502-6481085 (+)
C57BL/6NJ MGP_C57BL6NJ_G0023549
 protein coding gene Chr17:6786868-6807906 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0021059
 protein coding gene Chr17:7877141-7897518 (-)
CAST/EiJ MGP_CASTEiJ_G0022383
 protein coding gene Chr17:6460063-6482794 (+)
CBA/J MGP_CBAJ_G0022841
 protein coding gene Chr17:7039329-7061032 (+)
DBA/2J MGP_DBA2J_G0022974
 protein coding gene Chr17:6148678-6168885 (+)
FVB/NJ MGP_FVBNJ_G0022943
 protein coding gene Chr17:6078115-6097908 (+)
LP/J MGP_LPJ_G0023045
 protein coding gene Chr17:6316290-6337160 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0022963
 protein coding gene Chr17:6736835-6766674 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0023575
 protein coding gene Chr17:6486054-6507992 (+)
PWK/PhJ MGP_PWKPhJ_G0022131
 protein coding gene Chr17:5794513-5814570 (+)
SPRET/EiJ no annotation
WSB/EiJ MGP_WSBEiJ_G0022440
 protein coding gene Chr17:6781221-6803659 (+)



Homology
more
  • Human Ortholog
    C6orf118, chromosome 6 open reading frame 118
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    C6orf118, chromosome 6 open reading frame 118
  • Synonyms
    bA85G2.1, dJ416F21.2
  • Links
    NCBI Gene ID: 168090
    neXtProt AC: NX_Q5T5N4
    UniProt: Q5T5N4

  • Chr Location
    6q27
Human Diseases
less
  • References
    6 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotypes from 2 alleles in 2 genetic backgrounds
    3 phenotypes from multigenic genotypes
    363 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Males homozygous for a null allele show reduced male fertility and impaired sperm motility with asymmetric flagellar waveforms.
Gene Ontology
(GO)
Classifications
less
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

No experimental evidence to support Cellular Component annotation, following literature review. See J:73796.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    714
  • Tissues
    6
  • cDNA Data
    34
  • Literature Summary
    1
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 66931 NCBI Gene Model | MGI Sequence Detail 20000 C57BL/6J ±  kb
    transcript NM_025851 RefSeq | MGI Sequence Detail 1878 C57BL/6  
    polypeptide NP_001334473 RefSeq | MGI Sequence Detail 532 C57BL/6  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      9 Sequences
    • InterPro Domains
      IPR032755 Translin-associated factor X-interacting protein 1, N-terminal
    Molecular
    Reagents
    less
    • All nucleic 34
      cDNA 34

      Microarray probesets 4
    References
    more
    • Summaries
      All 382
      Developmental Gene Expression 1
      Diseases 6
      Phenotypes 363
    • Earliest
      J:7073 Washburn LL, et al., Sex reversal in XY mice caused by dominant mutation on chromosome 17. Nature. 1983 May 26;303(5915):338-40
    • Latest
      J:354984 Emili M, et al., Reversal of neurodevelopmental impairment and cognitive enhancement by pharmacological intervention with the polyphenol polydatin in a Down syndrome model. Neuropharmacology. 2024 Sep 27;261:110170
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    12/10/2024
    MGI 6.24     		The Jackson Laboratory