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Sh3d21 Gene Detail
Summary
  • Symbol
    Sh3d21
  • Name
    SH3 domain containing 21
  • Synonyms
    1700029G01Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1914188
    NCBI Gene: 66938
  • Alliance
    gene page
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr4:126044395-126057284 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 4, 59.97 cM, cytoband D2.1
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    340 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1914188
 protein coding gene Chr4:126044395-126057503 (-)
129S1/SvImJ MGP_129S1SvImJ_G0028773
 protein coding gene Chr4:127805862-127818756 (-)
A/J MGP_AJ_G0028732
 protein coding gene Chr4:122773609-122787704 (-)
AKR/J MGP_AKRJ_G0028685
 protein coding gene Chr4:126154484-126169078 (-)
BALB/cJ MGP_BALBcJ_G0028755
 protein coding gene Chr4:123356996-123369897 (-)
C3H/HeJ MGP_C3HHeJ_G0028469
 protein coding gene Chr4:126206082-126219385 (-)
C57BL/6NJ MGP_C57BL6NJ_G0029197
 protein coding gene Chr4:132689301-132702148 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0026470
 protein coding gene Chr4:115929801-115942968 (-)
CAST/EiJ MGP_CASTEiJ_G0027902
 protein coding gene Chr4:124323353-124336213 (-)
CBA/J MGP_CBAJ_G0028435
 protein coding gene Chr4:135899198-135912110 (-)
DBA/2J MGP_DBA2J_G0028584
 protein coding gene Chr4:123235534-123248435 (-)
FVB/NJ MGP_FVBNJ_G0028551
 protein coding gene Chr4:121884708-121898402 (-)
LP/J MGP_LPJ_G0028685
 protein coding gene Chr4:128092063-128104966 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0028577
 protein coding gene Chr4:140929606-140942499 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0029235
 protein coding gene Chr4:126501348-126514244 (-)
PWK/PhJ MGP_PWKPhJ_G0027623
 protein coding gene Chr4:119700232-119713525 (-)
SPRET/EiJ MGP_SPRETEiJ_G0027449
 protein coding gene Chr4:122323400-122337406 (-)
WSB/EiJ MGP_WSBEiJ_G0027982
 protein coding gene Chr4:126600064-126612927 (-)



Homology
more
  • Human Ortholog
    SH3D21, SH3 domain containing 21
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SH3D21, SH3 domain containing 21
  • Synonyms
    C1orf113
  • Links
    NCBI Gene ID: 79729
    neXtProt AC: NX_A4FU49
    UniProt: A4FU49

  • Chr Location
    1p34.3; chr1:36306368-36330236 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    10 phenotype references
Male mice homozygous for a null allele exhibit normal fertility.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    4
  • GO References
    2
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    10
  • Literature Summary
    1
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000073758 Ensembl Gene Model | MGI Sequence Detail 12890 C57BL/6J ±  kb
    transcript ENSMUST00000097891 Ensembl | MGI Sequence Detail 2384 Not Applicable  
    polypeptide ENSMUSP00000095501 Ensembl | MGI Sequence Detail 665 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 10
      cDNA 10

      Microarray probesets 3
    Other
    Accession IDs
    less
    MGI:2140452
    References
    more
    • Summaries
      All 35
      Developmental Gene Expression 1
      Gene Ontology 2
      Phenotypes 10
    • Earliest
      J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
    • Latest
      J:348447 Nguyen TTT, et al., Gene-deficient mouse model established by CRISPR/Cas9 system reveals 15 reproductive organ-enriched genes dispensable for male fertility. Frontiers in Cell and Developmental Biology. 2024;12
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    11/12/2024
    MGI 6.24     		The Jackson Laboratory