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Polr3k Gene Detail
Summary
  • Symbol
    Polr3k
  • Name
    polymerase (RNA) III (DNA directed) polypeptide K
  • Synonyms
    12.3kDa, 1500004O14Rik, C11, RPC10, RPC11
  • Feature Type
    protein coding gene
  • IDs
    MGI:1914255
    NCBI Gene: 67005
  • Alliance
    gene page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:181506153-181512623 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 2, 103.82 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    122 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1914255
 protein coding gene Chr2:181506130-181512623 (+)
129S1/SvImJ MGP_129S1SvImJ_G0027039
 protein coding gene Chr2:188495707-188502200 (+)
A/J MGP_AJ_G0027005
 protein coding gene Chr2:180716121-180722612 (+)
AKR/J MGP_AKRJ_G0026975
 protein coding gene Chr2:186142505-186148996 (+)
BALB/cJ MGP_BALBcJ_G0027013
 protein coding gene Chr2:181198227-181204720 (+)
C3H/HeJ MGP_C3HHeJ_G0026755
 protein coding gene Chr2:186482730-186489221 (+)
C57BL/6NJ MGP_C57BL6NJ_G0027459
 protein coding gene Chr2:193937727-193944220 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0024823
 protein coding gene Chr2:171400829-171407444 (+)
CAST/EiJ MGP_CASTEiJ_G0026214
 protein coding gene Chr2:184764793-184771475 (+)
CBA/J MGP_CBAJ_G0026732
 protein coding gene Chr2:200977914-200984407 (+)
DBA/2J MGP_DBA2J_G0026869
 protein coding gene Chr2:179818781-179825272 (+)
FVB/NJ MGP_FVBNJ_G0026835
 protein coding gene Chr2:178449241-178455734 (+)
LP/J MGP_LPJ_G0026971
 protein coding gene Chr2:188516160-188522653 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0026855
 protein coding gene Chr2:203508980-203515473 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0027519
 protein coding gene Chr2:186121433-186127926 (+)
PWK/PhJ MGP_PWKPhJ_G0025950
 protein coding gene Chr2:177350292-177357057 (+)
SPRET/EiJ MGP_SPRETEiJ_G0025750
 protein coding gene Chr2:182611758-182625686 (+)
WSB/EiJ MGP_WSBEiJ_G0026286
 protein coding gene Chr2:187093620-187100122 (+)



Homology
more
  • Human Ortholog
    POLR3K, RNA polymerase III subunit K
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    POLR3K, RNA polymerase III subunit K
  • Synonyms
    C11, C11-RNP3, HLD21, My010, RPC10, RPC11, RPC12.5
  • Links
    NCBI Gene ID: 51728
    neXtProt AC: NX_Q9Y2Y1
    UniProt: Q9Y2Y1

  • Chr Location
    16p13.3; chr16:46407-53608 (-)  GRCh38
Human Diseases
more
  • Diseases
    1 with human POLR3K associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    13
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    937
  • Tissues
    162
  • cDNA Data
    85
  • Literature Summary
    8
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 67005 NCBI Gene Model | MGI Sequence Detail 6471 C57BL/6J ±  kb
transcript NM_025901 RefSeq | MGI Sequence Detail 2925 C57BL/6  
polypeptide Q9CQZ7 UniProt | EBI | MGI Sequence Detail 108 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    3 Sequences
  • Protein Ontology
    PR:000013009 DNA-directed RNA polymerase III subunit RPC10
    (term hierarchy)
  • InterPro Domains
    IPR001529 DNA-directed RNA polymerase, M/15kDa subunit
    IPR019761 DNA-directed RNA polymerase M, 15kDa subunit, conserved site
    IPR012164 DNA-directed RNA polymerase subunit/transcription factor S
    IPR034014 Pol III subunit C11, C-terminal zinc ribbon
    IPR001222 Zinc finger, TFIIS-type
Molecular
Reagents
less
  • All nucleic 87
    cDNA 86
    Primer pair 1

    Microarray probesets 9
Other
Accession IDs
less
MGI:2138860, MGI:2144933
References
more
  • Summaries
    All 41
    Developmental Gene Expression 8
    Gene Ontology 5
    Phenotypes 5
  • Earliest
    J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
  • Latest
    J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory