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Tmem88 Gene Detail
Summary
  • Symbol
    Tmem88
  • Name
    transmembrane protein 88
  • Synonyms
    2600017H02Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1914270
    NCBI Gene: 67020
  • Alliance
    gene page
  • Transcription Start Sites
    7 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:69287345-69289060 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 11, 42.60 cM, cytoband B4
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    65 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1914270
 protein coding gene Chr11:69287342-69289060 (-)
129S1/SvImJ MGP_129S1SvImJ_G0018533
 protein coding gene Chr11:69825099-69826813 (-)
A/J MGP_AJ_G0018501
 protein coding gene Chr11:67198050-67199764 (-)
AKR/J MGP_AKRJ_G0018470
 protein coding gene Chr11:69208222-69209936 (-)
BALB/cJ MGP_BALBcJ_G0018473
 protein coding gene Chr11:67517051-67518765 (-)
C3H/HeJ MGP_C3HHeJ_G0018286
 protein coding gene Chr11:69226523-69228237 (-)
C57BL/6NJ MGP_C57BL6NJ_G0018924
 protein coding gene Chr11:71939030-71940745 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0016569
 protein coding gene Chr11:64126911-64128625 (-)
CAST/EiJ MGP_CASTEiJ_G0017841
 protein coding gene Chr11:69462480-69464194 (-)
CBA/J MGP_CBAJ_G0018259
 protein coding gene Chr11:75161314-75163028 (-)
DBA/2J MGP_DBA2J_G0018368
 protein coding gene Chr11:66788978-66790689 (-)
FVB/NJ MGP_FVBNJ_G0018358
 protein coding gene Chr11:66415908-66417622 (-)
LP/J MGP_LPJ_G0018438
 protein coding gene Chr11:70395210-70396924 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0018381
 protein coding gene Chr11:75774112-75775826 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0018966
 protein coding gene Chr11:69457417-69459131 (-)
PWK/PhJ MGP_PWKPhJ_G0017615
 protein coding gene Chr11:67432095-67433806 (-)
SPRET/EiJ MGP_SPRETEiJ_G0017405
 protein coding gene Chr11:69279382-69281089 (-)
WSB/EiJ MGP_WSBEiJ_G0017895
 protein coding gene Chr11:69136579-69138293 (-)



Homology
more
  • Human Ortholog
    TMEM88, transmembrane protein 88
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TMEM88, transmembrane protein 88
  • Links
    NCBI Gene ID: 92162
    neXtProt AC: NX_Q6PEY1
    UniProt: Q6PEY1

  • Chr Location
    17p13.1; chr17:7855066-7856099 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotype references
  • All Mutations and Alleles
    2
  • Chemically induced (other)
    1
  • Endonuclease-mediated
    1
  • Genomic Mutations
    1 involving Tmem88
  • Find Mice (IMSR)
    6 strains or lines available
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    15
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    23
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000045377 Ensembl Gene Model | MGI Sequence Detail 1716 C57BL/6J ±  kb
transcript ENSMUST00000050140 Ensembl | MGI Sequence Detail 1582 Not Applicable  
polypeptide ENSMUSP00000055528 Ensembl | MGI Sequence Detail 159 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 23
    cDNA 23

    Microarray probesets 3
References
more
  • Summaries
    All 30
    Developmental Gene Expression 1
    Gene Ontology 5
    Phenotypes 5
  • Earliest
    J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory