Pdzk1ip1 Gene Detail

Summary

• Symbol
  Pdzk1ip1
• Name
  PDZK1 interacting protein 1
• Synonyms
  0610007F13Rik, 2700030M23Rik, Map17

• Feature Type
  protein coding gene
• IDs
  MGI:1914432
  NCBI Gene: 67182
• Alliance
  gene page
• Transcription Start Sites
  12 TSS

Location &
Maps

• Sequence Map
  Chr4:114945905-114951091 bp, + strand

  From NCBI annotation of GRCm39
  

• View this region in JBrowse
  

• Genome Browsers
  Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 4, 52.75 cM
• Mapping Data
  3 experiments

Strain
Comparison

• SNPs within 2kb
  210 from dbSNP Build 142
• Strain Annotations
  18

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_1914432	protein coding gene	Chr4:114945905-114951096 (+)
129S1/SvImJ	MGP_129S1SvImJ_G0028595	protein coding gene	Chr4:115857583-115862776 (+)
A/J	MGP_AJ_G0028557	protein coding gene	Chr4:111449707-111454897 (+)
AKR/J	MGP_AKRJ_G0028505	protein coding gene	Chr4:113744414-113749598 (+)
BALB/cJ	MGP_BALBcJ_G0028577	protein coding gene	Chr4:112076340-112081532 (+)
C3H/HeJ	MGP_C3HHeJ_G0028291	protein coding gene	Chr4:115362739-115367928 (+)
C57BL/6NJ	MGP_C57BL6NJ_G0029021	protein coding gene	Chr4:120339813-120344997 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0026305	protein coding gene	Chr4:105520159-105537705 (+)
CAST/EiJ	MGP_CASTEiJ_G0027728	protein coding gene	Chr4:112781297-112786511 (+)
CBA/J	MGP_CBAJ_G0028259	protein coding gene	Chr4:123460870-123466072 (+)
DBA/2J	MGP_DBA2J_G0028408	protein coding gene	Chr4:112079812-112085002 (+)
FVB/NJ	MGP_FVBNJ_G0028376	protein coding gene	Chr4:110552528-110557724 (+)
LP/J	MGP_LPJ_G0028509	protein coding gene	Chr4:116066112-116071301 (+)
NOD/ShiLtJ	MGP_NODShiLtJ_G0028401	protein coding gene	Chr4:128597253-128602454 (+)
NZO/HlLtJ	MGP_NZOHlLtJ_G0029057	protein coding gene	Chr4:114991833-114997022 (+)
PWK/PhJ	MGP_PWKPhJ_G0027453	protein coding gene	Chr4:108876639-108881828 (+)
SPRET/EiJ	MGP_SPRETEiJ_G0027277	protein coding gene	Chr4:111390004-111395223 (+)
WSB/EiJ	MGP_WSBEiJ_G0027806	protein coding gene	Chr4:114773043-114778405 (+)

Homology

• Human Ortholog
  PDZK1IP1, PDZK1 interacting protein 1

• Vertebrate Orthologs
  3

Vertebrate Orthology Source

Alliance of Genome Resources

• Human Ortholog
  PDZK1IP1, PDZK1 interacting protein 1
  
• Synonyms
  DD96, MAP17, SPAP
• Links
  HGNC:16887

  NCBI Gene ID: 10158

  neXtProt AC: NX_Q13113

  UniProt: Q13113

  
  
• Chr Location
  1p33; chr1:47183582-47191044 (-)  GRCh38

---

• MGI Vertebrate Homology
  Pdzk1ip1 stringent orthology
  1 human;1 mouse;1 rat;1 zebrafish
  
• HCOP
  vertebrate homology predictions: PDZK1IP1
• Gene Tree
  Pdzk1ip1
  

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  10 phenotype references
  

• All Mutations and Alleles
  9
• Chemically induced (other)
  2
• Endonuclease-mediated
  3
• Radiation induced
  1
• Targeted
  3
• Genomic Mutations
  4 involving Pdzk1ip1
• Incidental Mutations
  APF , CvDC
• Find Mice (IMSR)
  13 strains or lines available
• Recombinase Activity
  Comparison Matrix Gene Expression + Recombinase Activity

Gene Ontology
(GO)
Classifications

• All GO Annotations
  1
• GO References
  1

Expression

• Assay Results
  753
• Tissues
  35
• cDNA Data
  72
• Literature Summary
  4

Images

Tissue x Stage Matrix

• Other Mouse Links
  Allen Institute
  GENSAT
  GEO
  Expression Atlas
• Other Vertebrate Links
  Xenbase pdzk1ip1
  ZFIN pdzk1ip1

Sequences &
Gene Models

• All Sequences
  56
• RefSeq
  8
• UniProt
  3
• CCDS
  CCDS18487.1, CCDS51272.1

• Ensembl
  ENSMUSG00000028716 (Evidence)
• NCBI Gene
  67182

Representative Sequences			Length	Strain/Species
genomic	67182	NCBI Gene Model | MGI Sequence Detail	5187	C57BL/6J
transcript	NM_001164557	RefSeq | MGI Sequence Detail	1129	C57BL/6
polypeptide	Q9CQH0	UniProt | EBI | MGI Sequence Detail	114	Not Applicable

Protein
Information

• UniProt
  3 Sequences
• Protein Ontology
  PR:000012529 PDZK1-interacting protein 1
  (term hierarchy)
• InterPro Domains
  IPR031627 PDZK1-interacting protein 1/SMIM24

Molecular
Reagents

• All nucleic 75

  cDNA 74

  Other 1

  
  

  Microarray probesets 4

Other
Accession IDs

MGI:1918913, MGI:2140501

References

• Summaries
  All 38

  Developmental Gene Expression 4

  Gene Ontology 1

  Phenotypes 10
• Earliest
  J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
• Latest
  J:326541 Cyagen Biosciences Inc., Cyagen Biosciences Website. 2022;

TSS for Pdzk1ip1:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr38446	Chr4:114945931-114945966 (+)	44 bp
Tssr38447	Chr4:114945976-114945987 (+)	77 bp
Tssr38448	Chr4:114946060-114946069 (+)	160 bp
Tssr38449	Chr4:114946102-114946106 (+)	199 bp
Tssr38450	Chr4:114946111-114946122 (+)	212 bp
Tssr38451	Chr4:114946187-114946346 (+)	362 bp
Tssr38452	Chr4:114946352-114946356 (+)	449 bp
Tssr38453	Chr4:114947357-114947362 (+)	1,455 bp
Tssr38454	Chr4:114947365-114947366 (+)	1,461 bp
Tssr38455	Chr4:114947385-114947425 (+)	1,500 bp
Tssr1267	Chr4:114948193-114948203 (+)	2,293 bp
Tssr38456	Chr4:114950779-114950805 (+)	4,887 bp