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Ndufa13 Gene Detail
Summary
  • Symbol
    Ndufa13
  • Name
    NADH:ubiquinone oxidoreductase subunit A13
  • Synonyms
    2700054G14Rik, CDA016, CGI-39, Grim19, GRIM-19
  • Feature Type
    protein coding gene
  • IDs
    MGI:1914434
    NCBI Gene: 67184
  • Alliance
    gene page
  • Transcription Start Sites
    6 TSS
Location &
Maps
more
  • Sequence Map
    Chr8:70346830-70355208 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 8, 34.03 cM, cytoband C1
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    271 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1914434
 protein coding gene Chr8:70346813-70355208 (-)
129S1/SvImJ MGP_129S1SvImJ_G0033682
 protein coding gene Chr8:70123300-70131480 (-)
A/J MGP_AJ_G0033665
 protein coding gene Chr8:67275417-67283922 (-)
AKR/J MGP_AKRJ_G0033590
 protein coding gene Chr8:69181929-69190113 (-)
BALB/cJ MGP_BALBcJ_G0033661
 protein coding gene Chr8:67501546-67510082 (-)
C3H/HeJ MGP_C3HHeJ_G0033371
 protein coding gene Chr8:69843212-69851334 (-)
C57BL/6NJ MGP_C57BL6NJ_G0034178
 protein coding gene Chr8:72791280-72799664 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0031122
 protein coding gene Chr8:62099418-62108198 (-)
CAST/EiJ MGP_CASTEiJ_G0032696
 protein coding gene Chr8:69307970-69316179 (-)
CBA/J MGP_CBAJ_G0033349
 protein coding gene Chr8:75429210-75437355 (-)
DBA/2J MGP_DBA2J_G0033503
 protein coding gene Chr8:67001737-67010315 (-)
FVB/NJ MGP_FVBNJ_G0033444
 protein coding gene Chr8:66098368-66106966 (-)
LP/J MGP_LPJ_G0033590
 protein coding gene Chr8:70173611-70181791 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0033488
 protein coding gene Chr8:78086449-78094828 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0034196
 protein coding gene Chr8:69363904-69372985 (-)
PWK/PhJ MGP_PWKPhJ_G0032404
 protein coding gene Chr8:66286429-66294945 (-)
SPRET/EiJ MGP_SPRETEiJ_G0032240
 protein coding gene Chr8:68340165-68349722 (-)
WSB/EiJ MGP_WSBEiJ_G0032811
 protein coding gene Chr8:69732838-69742025 (-)



Homology
more
  • Human Ortholog
    NDUFA13, NADH:ubiquinone oxidoreductase subunit A13
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    NDUFA13, NADH:ubiquinone oxidoreductase subunit A13
  • Synonyms
    B16.6, CDA016, CGI-39, GRIM-19, GRIM19, MC1DN28
  • Links
    NCBI Gene ID: 51079
    neXtProt AC: NX_Q9P0J0
    UniProt: Q9P0J0

  • Chr Location
    19p13.11; chr19:19515736-19529054 (+)  GRCh38
Human Diseases
more
  • Diseases
    2 with human NDUFA13 associations

Human Disease Mouse Models
      
IDs
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    19 phenotypes from 2 alleles in 2 genetic backgrounds
    11 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Homozygous null mice display embryonic lethality, failed gastrulation, absent organogenesis, small and abnormal inner cell mass and trophoblast, and abnormal mitochondria. Mice heterozygous for a different allele exhibit oligospermia, asthenozoospermia, and increased oxidative stress and apoptosis in sperm.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    44
  • GO References
    12
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    846
  • Tissues
    131
  • cDNA Data
    163
  • Literature Summary
    7
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000036199 Ensembl Gene Model | MGI Sequence Detail 8379 C57BL/6J ±  kb
    transcript ENSMUST00000110167 Ensembl | MGI Sequence Detail 1251 Not Applicable  
    polypeptide ENSMUSP00000105796 Ensembl | MGI Sequence Detail 144 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 164
      cDNA 163
      Primer pair 1

      Microarray probesets 3
    Other
    Accession IDs
    less
    MGI:2142700
    References
    more
    • Summaries
      All 57
      Developmental Gene Expression 7
      Gene Ontology 12
      Phenotypes 11
    • Earliest
      J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
    • Latest
      J:355679 Vercellino I, et al., SCAF1 drives the compositional diversity of mammalian respirasomes. Nat Struct Mol Biol. 2024 Jul;31(7):1061-1071
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    11/12/2024
    MGI 6.24     		The Jackson Laboratory