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Uqcc2 Gene Detail
Summary
  • Symbol
    Uqcc2
  • Name
    ubiquinol-cytochrome c reductase complex assembly factor 2
  • Synonyms
    2900010M23Rik, Cbp6, Mnf1
  • Feature Type
    protein coding gene
  • IDs
    MGI:1914517
    NCBI Gene: 67267
  • Alliance
    gene page
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr17:27341639-27352865 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 17, 13.75 cM, cytoband B1
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    285 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1914517
 protein coding gene Chr17:27341637-27352890 (-)
129S1/SvImJ MGP_129S1SvImJ_G0023417
 protein coding gene Chr17:26373133-26384387 (-)
A/J MGP_AJ_G0023374
 protein coding gene Chr17:25567248-25578489 (-)
AKR/J MGP_AKRJ_G0023340
 protein coding gene Chr17:25706989-25718243 (-)
BALB/cJ MGP_BALBcJ_G0023379
 protein coding gene Chr17:25810156-25821410 (-)
C3H/HeJ MGP_C3HHeJ_G0023140
 protein coding gene Chr17:26081384-26092625 (-)
C57BL/6NJ MGP_C57BL6NJ_G0023822
 protein coding gene Chr17:27490798-27502051 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0021296
 protein coding gene Chr17:22970492-22982090 (-)
CAST/EiJ MGP_CASTEiJ_G0022641
 protein coding gene Chr17:26010855-26022122 (-)
CBA/J MGP_CBAJ_G0023114
 protein coding gene Chr17:28444399-28455639 (-)
DBA/2J MGP_DBA2J_G0023246
 protein coding gene Chr17:25129389-25140630 (-)
FVB/NJ MGP_FVBNJ_G0023215
 protein coding gene Chr17:24907820-24919074 (-)
LP/J MGP_LPJ_G0023323
 protein coding gene Chr17:26621440-26632694 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0023233
 protein coding gene Chr17:27959302-27970556 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0023863
 protein coding gene Chr17:26081357-26092617 (-)
PWK/PhJ MGP_PWKPhJ_G0022391
 protein coding gene Chr17:23923158-23934480 (-)
SPRET/EiJ MGP_SPRETEiJ_G0022209
 protein coding gene Chr17:24125652-24137046 (-)
WSB/EiJ MGP_WSBEiJ_G0022704
 protein coding gene Chr17:26108064-26119317 (-)



Homology
more
  • Human Ortholog
    UQCC2, ubiquinol-cytochrome c reductase complex assembly factor 2
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    UQCC2, ubiquinol-cytochrome c reductase complex assembly factor 2
  • Synonyms
    bA6B20.2, C6orf125, C6orf126, Cbp6, M19, MC3DN7, MNF1
  • Links
    NCBI Gene ID: 84300
    neXtProt AC: NX_Q9BRT2
    UniProt: Q9BRT2

  • Chr Location
    6p21.31
Human Diseases
more
  • Diseases
    1 with human UQCC2 associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    20
  • GO References
    6
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    92
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 67267 NCBI Gene Model | MGI Sequence Detail 11227 C57BL/6J ±  kb
transcript NM_026063 RefSeq | MGI Sequence Detail 473 C57BL/6  
polypeptide Q9CQY6 UniProt | EBI | MGI Sequence Detail 136 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    3 Sequences
  • Protein Ontology
    PR:000032445 ubiquinol-cytochrome c reductase complex assembly factor 2
    (term hierarchy)
  • InterPro Domains
    IPR046827 Complex III assembly factor UQCC2/CBP6
    IPR037698 Ubiquinol-cytochrome-c reductase complex assembly factor 2
Molecular
Reagents
less
  • All nucleic 92
    cDNA 92

    Microarray probesets 4
References
more
  • Summaries
    All 34
    Developmental Gene Expression 1
    Gene Ontology 6
    Phenotypes 6
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:275567 Zurkirchen L, et al., Yin Yang 1 sustains biosynthetic demands during brain development in a stage-specific manner. Nat Commun. 2019 May 16;10(1):2192
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory